@DrAGreenland Avatar @DrAGreenland Dr Andrew Greenland

Dr Andrew Greenland posts on X about health, this is, brain, in the the most. They currently have [-----] followers and [---] posts still getting attention that total [------] engagements in the last [--] hours.

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Social Influence

Social category influence countries 100% finance 10% currencies 1% travel destinations 1% stocks 1% social networks 1%

Social topic influence health #2391, this is 7%, brain #1849, in the 7%, dr 6%, truth 5%, food 4%, more than 4%, matter 4%, feels 3%

Top accounts mentioned or mentioned by @dawhiterhino @dankatriley @foundmyfitness @buzzsprout @lagangjoshua6 @lucidbrot @natetures @rbxer @cherrychatonne @tanimal__ @boilermakerkev @seismosue @muscleforlife @ravenloft43 @mmacy153 @joanbandy @milliondolrsmle @gidigba @1nocagal @cuzzindennis619

Top Social Posts

Top posts by engagements in the last [--] hours

"UK medical doctor practising functional medicine with a clinical focus on brain health cognitive decline and clinical AI. My work is grounded in root-cause medicine asking why systems fail not just what label to apply. Thats why I use the Bredesen ReCODE Protocol: it treats cognitive decline as a multi-factor problem not a single-drug deficiency. This is functional medicine without the woo: Biochemistry over buzzwords Physiology before protocols Evidence where it exists judgement where it doesnt I work with people who want: Prevention not polite neglect Coherence not checklists Explanations"
X Link 2025-12-14T16:32Z [----] followers, [----] engagements

"Many people say I feel more concrete than I used to. Abstract thinking - ideas hypotheticals long-range planning - feels heavier than practical tasks. Clinically abstraction is one of the first things to narrow when cognitive bandwidth tightens. This is adaptive not pathological. The brain prioritises whats actionable when capacity is limited. #CognitiveHealth #ClinicalInsight"
X Link 2026-02-10T19:40Z [----] followers, [---] engagements

"When thinking gets stuck instead of tired 1/ Not all mental fatigue is about exhaustion"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"3/ Thoughts repeat instead of progressing"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"A common complaint isnt poor decisions its distrust of decisions already made. When thinking feels effortful confidence drops even if accuracy hasnt. Helping people recalibrate confidence - rather than improving decisions - often restores decisiveness surprisingly quickly. #Cognition #BrainFunctionp"
X Link 2026-02-13T20:34Z [----] followers, [---] engagements

"A few things happening here worth unpacking: This is selection bias in a single image. Young active people at a beach in the 1960s-70s look like young active people at a beach in [----]. Nobodys posting the coronary artery disease wards from the same era. They ate more drank more & smoked more - and died younger because of it. Age-adjusted heart disease mortality has dropped 60% since the 1960s. We didnt get sicker. We got better at not dying AND better at diagnosing whats wrong. What DID change Ultra-processed food availability sedentary jobs chronic stress and sleep disruption are real"
X Link 2026-02-14T10:35Z [----] followers, 10.3K engagements

"Many cognitive changes are negotiations not failures. The brain adjusting how much it holds how fast it moves and how widely it scans. When we stop interpreting these negotiations as loss people often regain trust in their thinking - and trust is one of the strongest stabilisers cognition has. #Cognition #HealthyAgeing"
X Link 2026-02-15T08:26Z [----] followers, [---] engagements

"Vitamin D matters - no argument there. 35% of US adults are insufficient and it genuinely influences immune function bone health and mood regulation. But theres a big gap between vitamin D is important and take [-----] IU daily because your head is sweating. The Endocrine Society caps general supplementation at [----] IU/day. Higher therapeutic doses exist but require monitored serum 25(OH)D levels - because vitamin D is fat-soluble accumulates and can cause real harm in excess (hypercalcemia nephrolithiasis). The bigger issue: every symptom listed here - fatigue brain fog panic joint pain low"
X Link 2026-02-15T08:53Z [----] followers, [---] engagements

"Its right there on the label: 26g of added sugars which is 53% of your daily value in a single can. The fact that you cant identify that as unhealthy is more concerning than the Red Bull itself. No single ingredient needs to be toxic for a product to be unhealthy. A can of liquid that is essentially carbonated water + 26g of sugar + caffeine with zero fiber fat or protein to blunt the glycemic response isnt harmful because of some mystery chemical - its harmful because of what it is: a rapid-absorption sugar delivery system. The vitamins on the label dont offset that. Youre not deficient in"
X Link 2026-02-15T11:01Z [----] followers, [---] engagements

"This is a great example of how a real paper gets weaponized on social media. The Valk et al. paper raises legitimate questions about oversimplified dietary guidelines - but its a narrative review meaning the authors chose which studies to discuss. Its not a systematic review or meta-analysis with predefined inclusion criteria. Heres whats actually well-established: the health impact of saturated fat depends almost entirely on what replaces it. Swap it for refined carbs and sugar No benefit (and possibly worse outcomes). Swap it for polyunsaturated fats Consistent cardiovascular benefit across"
X Link 2026-02-15T11:06Z [----] followers, [---] engagements

"Theres a solid foundation here - resistance training protein sleep walking and stress management are genuinely the highest-yield health behaviors. No argument there. Where this thread gets sloppy is in the details. The cold plunge research on hypertrophy (Roberts et al. 2015) specifically looked at cold water immersion immediately post-resistance training. Thats a narrow finding being applied broadly. Theres separate literature showing benefits for inflammation mood and autonomic regulation in other contexts. The CGM point conflates misuse with the tool itself. Continuous glucose data has"
X Link 2026-02-15T14:59Z [----] followers, [----] engagements

"The food list itself is solid - these are nutrient-dense minimally processed whole foods and most people would benefit from eating more of them. No argument there. The problem is the leap from good food choices to guaranteed fat loss muscle gain and 10X energy. These are three distinct physiological outcomes governed by different mechanisms: Fat loss requires a sustained caloric deficit. You can absolutely gain fat eating avocados steak and Greek yogurt - theyre calorie-dense foods. A person eating [----] calories of this list at a [----] TDEE will store fat regardless of food quality. Muscle"
X Link 2026-02-15T16:19Z [----] followers, [----] engagements

"Cool diagram. Its from a mouse study on gut dysbiosis and social dominance behavior in rodents. What it doesnt show: that drinking a zero-calorie soda makes you a loser in human social hierarchies. Mice establish dominance through tube tests. Youre not a mouse. Your social standing isnt determined by butyric acid levels and HDAC2 expression in the mPFC. Its determined by about a thousand variables that dont exist in a cage. The sweetener-dysbiosis link is also far more nuanced than presented - effects are dose-dependent sweetener-specific and inconsistent across studies. But nuance doesnt get"
X Link 2026-02-15T16:34Z [----] followers, [--] engagements

"The lion also doesnt live past [--] cant plan for retirement and has never had to navigate a custody dispute a mortgage or a cancer diagnosis. Children at play also cry when theyre tired quit when theyre frustrated and have zero responsibilities. Theyre not evidence that difficulty is an illusion - theyre evidence that low-stakes environments with no consequences feel easier. Which is obvious. The moment you give a child a task with real pressure - a timed test a recital in front of strangers a sport where losing matters to them - stress shows up immediately. No one had to teach them that."
X Link 2026-02-15T16:58Z [----] followers, [---] engagements

"Fantastic conversation - this episode highlights how the fundamentals of metabolic health converge. As Dr. Patrick and Dr. Attia discussed optimal protein intake is about more than muscle; its about maintaining mitochondrial function neurotransmitter balance and immune resilience with age. Creatine bridges that gap beautifully - supporting both muscular strength and cognitive energy through enhanced ATP recycling. And sauna therapy acts as a form of hormetic stress activating heat-shock proteins improving endothelial function and mimicking cardiovascular exercise. In functional medicine these"
X Link 2025-10-21T00:09Z [----] followers, [----] engagements

"This list mixes some legitimate stress-related symptoms with conditions that have complex multifactorial causes and the advice section oversimplifies things significantly. Whats reasonable here: Chronic stress genuinely does affect sleep blood sugar regulation immune function inflammation and cortisol-driven fat distribution. And some of the advice is solid - exercise social support and reducing exposure to anxiety-inducing media are well-supported stress management strategies. Where it goes off track: Lumping conditions like gallstones osteoporosis sleep apnea and autoimmune diseases under"
X Link 2026-02-07T21:59Z [----] followers, [--] engagements

"These four map neatly onto the research. Protein does far more than build muscle - it regulates hunger and prevents age-related decline. Resistance training may be the most underutilized longevity intervention we have. Sleep is the multiplier that makes the other habits actually work. And kindness isnt soft - prosocial behavior and strong social bonds are among the most powerful predictors of longevity weve found. The real insight is these arent four separate habits. They form a self-reinforcing loop which is why the rest works itself out isnt nave - its how compounding systems actually"
X Link 2026-02-08T00:26Z [----] followers, [--] engagements

"This sounds logical but misses the actual pharmacology. GLP-1 agonists dont just reduce appetite - they improve insulin sensitivity slow gastric emptying reduce hepatic glucose output and appear to downregulate food noise at the neurological level. Two people eating identical calories can have vastly different metabolic outcomes depending on hormonal signaling insulin resistance and nutrient partitioning. The just eat less framing assumes metabolism is a simple math equation. It isnt"
X Link 2026-02-10T00:49Z [----] followers, 118K engagements

"Worth noting what significantly associated actually means here. Statistical significance clinical magnitude. The effect sizes matter enormously. Most of these associations are confounded by what researchers call the healthy user bias - people who choose plant-based diets also tend to exercise more smoke less drink less and engage more with preventive healthcare. The better-designed studies that control for these variables still show benefit but the gap narrows considerably. The real takeaway isnt meat bad - its that higher fiber intake greater phytonutrient diversity and lower ultra-processed"
X Link 2026-02-10T00:52Z [----] followers, [---] engagements

"The regulatory consensus is worth noting but no credible signal oversimplifies things. The IARC 2A classification (probable carcinogen) wasnt based on nothing - it was based on mechanistic and animal data. The disagreement is about whether real-world dietary exposure reaches levels that matter clinically. Whats more interesting than the cancer debate: Glyphosates impact on the gut microbiome via the shikimate pathway (which our bacteria DO have) Potential endocrine disruption at low doses - something traditional toxicology models werent designed to capture Surfactants in commercial"
X Link 2026-02-10T00:59Z [----] followers, [---] engagements

"Castor oil is a decent skin moisturizer. Thats about where the evidence stops and the marketing begins. Lets go claim by claim: Boosts collagen - No human clinical trials support this. Ricinoleic acid has shown anti-inflammatory properties in vitro and in animal models but boosts collagen production is a leap the literature hasnt made. Natures Botox - Botox paralyzes muscles to reduce wrinkles. Castor oil sits on top of your skin and traps moisture. These are not comparable mechanisms. Calling it natures Botox is like calling a Band-Aid natures surgery. Stimulate new hair growth - One 2003"
X Link 2026-02-14T12:54Z [----] followers, [--] engagements

"@foundmyfitness Appreciate the honesty on NR/NMN - mechanistically plausible but unproven in humans should be the default framing until the trial data catches up. The real headline here is that consistent exercise is doing more for your NAD biology than any supplement currently can"
X Link 2026-02-14T17:48Z [----] followers, [--] engagements

"Decision difficulty often comes from too many thoughts arriving at once - not from poor reasoning. When the brain cant queue effectively everything competes for attention simultaneously. Creating sequence - what comes first what can wait - restores clarity without changing the decisions themselves. #Cognition #BrainFunction"
X Link 2026-02-07T10:42Z [----] followers, [---] engagements

"An early signal I often see is slower recovery after mentally demanding days. People still cope - but need more time to feel themselves again. This isnt fragility. Its a sign the brains recovery window has widened. When recovery is protected baseline function often improves without further intervention. #BrainHealth #ClinicalInsight"
X Link 2026-02-07T18:02Z [----] followers, [---] engagements

"Cognitive change is often the brain negotiating sustainability. Less excess. Fewer simultaneous demands. More rhythm. When we align with this negotiation instead of fighting it thinking often becomes steadier - not sharper not faster but more reliable. And reliability is what most people are actually missing. #Cognition #HealthyAgeing"
X Link 2026-02-08T11:57Z [----] followers, [---] engagements

"Cognitive change is often the brain negotiating sustainability. Less excess. Fewer simultaneous demands. More rhythm. When we align with this negotiation instead of fighting it thinking often becomes steadier - not sharper not faster but more reliable. And reliability is what most people are actually missing. #Cognition #HealthyAgeing"
X Link 2026-02-08T11:57Z [----] followers, [---] engagements

"1000+ papers and yet the headline claim rests on a single acute study in sleep-deprived subjects. Creatine likely does benefit cognition - especially in vegetarians and under stress. Thats supported. But brain uptake is rate-limited by SLC6A8 transport. Taking 20g doesnt mean your brain gets 4x more than at 5g - it means your kidneys and GI tract handle the surplus. The 911% brain creatine increases cited come from multi-day loading protocols not single doses. And the ISSN safety data covers 35g/day - not chronic dosing at 1520g which simply hasnt been studied long-term. Interesting"
X Link 2026-02-13T20:56Z [----] followers, [--] engagements

"Dr. Simpson nailed this but let me add some numbers to the frame. The claim: hospitals are flooded with GLP-1 side effects and we cant see it because the US lacks centralized data. The reality: The US has FAERS (FDA Adverse Event Reporting System) insurance claims databases covering hundreds of millions of patients the Sentinel System actively monitoring 100M+ lives and post-market surveillance from the SELECT and STEP trial programs. The idea that a catastrophic safety signal could hide in this infrastructure is not credible. Do GLP-1 agonists have side effects Yes - nausea gastroparesis"
X Link 2026-02-14T13:04Z [----] followers, [---] engagements

"This is a textbook example of confusing correlation with causation. India and Hong Kong differ in GDP per capita healthcare infrastructure sanitation air quality infectious disease burden poverty rates and access to clean water. Attributing a 15.5-year life expectancy gap to meat vs no meat is like saying umbrellas cause rain because you see them together. You can make a strong case for including quality animal protein in your diet without needing to use misleading comparisons to do it. https://twitter.com/i/web/status/2022828051457794432 https://twitter.com/i/web/status/2022828051457794432"
X Link 2026-02-15T00:19Z [----] followers, [--] engagements

"6/ When people pace before fatigue hits thinking quality often stabilises"
X Link 2026-02-05T08:35Z [----] followers, [--] engagements

"7/ Preserving endurance protects ability. #BrainFunction #Cognition #ClinicalInsight"
X Link 2026-02-05T08:35Z [----] followers, [--] engagements

"Some people worry when it takes longer to get started mentally. The thought arrives - but after a pause. This delay is often misread as loss. Clinically its more like a slower ignition. Once the engine is running thinking is often intact. Respecting the pause usually shortens it over time. #BrainHealth #CognitiveHealth https://twitter.com/i/web/status/2019739258567725113 https://twitter.com/i/web/status/2019739258567725113"
X Link 2026-02-06T11:45Z [----] followers, [---] engagements

"Some people worry when insight feels rarer - fewer aha moments fewer spontaneous connections. Insight depends on relaxed integration. When the brain is busy managing load it deprioritises creative synthesis. Insight usually returns after stability not before it. #BrainHealth #CognitiveHealth"
X Link 2026-02-12T14:02Z [----] followers, [---] engagements

"2/ Some people feel mentally stuck rather than drained"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"6/ Small shifts that restore movement often reduce rumination quickly"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"4/ This isnt anxiety by default its reduced cognitive momentum"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"7/ Progress matters more than depth when momentum is low. #BrainFunction #Cognition #ClinicalInsight"
X Link 2026-02-11T13:43Z [----] followers, [--] engagements

"Theres a kernel of truth here wrapped in unnecessary alarm. Yes as GLP-1 agonists come off the FDA shortage list compounding pharmacies will lose their authorization to produce those specific molecules. Novo Nordisk and Lilly have been aggressively pursuing this and the regulatory direction is clear. But compounding pharmacies operating under 503A/503B arent gray market - theyre federally regulated entities. Losing authorization for one molecule doesnt make them illegal. And enforcement has historically been targeted at bad actors not blanket shutdowns. Worth watching closely but take any bet"
X Link 2026-02-13T20:48Z [----] followers, [----] engagements

"People often begin avoiding multi-step or layered tasks - not because they cant do them but because holding the full structure feels heavy. This is an early protective behaviour. When complexity tolerance returns engagement usually follows without prompting or pressure. #BrainHealth #ClinicalInsight"
X Link 2026-02-14T10:32Z [----] followers, [---] engagements

"Some of these are legitimate clinical signs. Most are massive oversimplifications with a convenient funnel into keto and IF as the answer to everything. Bloodshot eyes could be [--] different things. Dark circles are usually genetic. And recommending natural antibiotics for Cushing syndrome is genuinely irresponsible - thats an endocrine condition requiring proper investigation not garlic and oregano. https://twitter.com/i/web/status/2022827194213712346 https://twitter.com/i/web/status/2022827194213712346"
X Link 2026-02-15T00:16Z [----] followers, [----] engagements

"I just published the 100th episode of Voices in Health and Wellness on @buzzsprout https://www.buzzsprout.com/2489689/achievements/1524184milestone=100 https://www.buzzsprout.com/2489689/achievements/1524184milestone=100"
X Link 2026-02-15T16:15Z [----] followers, [--] engagements

"Read the abstract more carefully. The strongest effects were in dog owners who also exercised regularly (OR 0.37) and werent socially isolated (OR 0.41). Dogs dont protect against dementia. Daily walks outdoor time social interaction and structured routines do. Dog ownership just forces all of those behaviors simultaneously. The cat finding confirms it - cats dont require walks or outdoor social routines and showed no protective signal. Thats not a cat problem. Its evidence that the mechanism is the activity package not the animal. People healthy enough to care for a dog are also less likely"
X Link 2026-02-15T19:25Z [----] followers, [----] engagements

"Im sorry about your family members. That kind of loss is real and I wont minimize it. I want to be careful here because there are personal experiences and public health claims mixed together and they need different responses. On the personal level: I cant evaluate individual medical cases through social media and neither can anyone else in this thread. If adverse events were documented by physicians at a major hospital thats between your family and their medical team. On the public claims: The more doses more Covid narrative misrepresents studies that showed waning vaccine effectiveness"
X Link 2026-02-15T19:51Z [----] followers, [----] engagements

"A subtle cognitive shift people notice is difficulty seeing the pattern in information they already understand. The details are there - but the organising thread feels harder to grasp. This isnt loss of intelligence. Pattern recognition relies on mental space. When that space narrows the brain focuses on pieces rather than the whole. Restore space and patterns often re-emerge without retraining. #BrainHealth #Cognition"
X Link 2026-02-09T21:45Z [----] followers, [---] engagements

"This is one of the most dangerous pieces of medical misinformation circulating online. People who avoid biopsies because of posts like this die of treatable cancers. First the source. Dr. Adiel Tel-Oren is not licensed to practice medicine in the United States. His MD is from a Russian university licensed only in Europe. He surrendered his US chiropractic license in [----] during a regulatory investigation and the Minnesota Board of Medical Practice sued him for unauthorized practice of medicine. He operates as a licensed nutritionist. He is not an oncologist pathologist or surgeon. Now the"
X Link 2026-02-15T23:11Z [----] followers, [---] engagements

"Interesting signal - and a useful reminder that oxidative stress is not a side-issue in rheumatoid arthritis its central to the pathology. A few clinical nuances worth adding from practice: Form matters. Many trials used synthetic -tocopherol. In real patients mixed tocopherols tocotrienols often perform better and avoid displacing -tocopherol which also has anti-inflammatory effects. Vitamin E works upstream not instead of DMARDs. Ive seen it reduce pain stiffness and CRP meaningfully - but it works best as part of a barrier-repair + redox + immune-modulation strategy not as a stand-alone"
X Link 2026-01-08T13:24Z [---] followers, [--] engagements

"There is something real here - but the magic isnt jumping stops ageing its mechanical signalling. In clinical practice the people who age fastest are the ones who stop exposing their tissues to impact oscillation and load. Bones lymph mitochondria fascia and even immune cells all rely on mechanotransduction to stay functional. Rebounding (or gentle jumping skipping hopping even brisk stair work) does a few things well: Lymphatic flow the lymph system has no pump; alternating compression and decompression matters. Bone signalling short bursts of impact stimulate osteocytes far more effectively"
X Link 2026-01-08T13:27Z [---] followers, [----] engagements

"This is one of those topics where polarisation does real harm. From clinical practice the truth sits between the extremes. A few key clarifications that matter: Cholesterol is biologically essential - no argument there. Cell membranes steroid hormones bile acids immune defence. Low cholesterol can indeed be a marker of illness frailty cancer chronic inflammation or malnutrition. Observational studies that link very low cholesterol with worse outcomes often reflect reverse causation not drug toxicity per se. LDL cardiovascular risk in isolation. LDL becomes problematic in a specific biological"
X Link 2026-01-08T22:13Z [---] followers, [---] engagements

"Theres a genuine signal here and its one I use selectively in practice - but with a few important nuances. Thymoquinone is interesting because it doesnt just block inflammation downstream like NSAIDs; it modulates upstream immune signalling including NF-B TNF- COX-2 and oxidative stress pathways. Thats why benefits show up across joints airways metabolic markers and even insulin sensitivity in some patients. Where it tends to work best clinically: Low-grade chronic inflammation (metabolic syndrome arthralgia allergic phenotypes) Patients who cant tolerate NSAIDs As an adjunct not a"
X Link 2026-01-09T10:41Z [----] followers, [---] engagements

"Completely agree - and in clinic this is exactly what separates robust health from endless tinkering. Most people dont fail because they lack information; they fail because their physiology never gets a chance to stabilise. These boring fundamentals quietly normalise insulin signalling circadian rhythm autonomic tone and inflammation - which then makes everything else easier. When patients nail: regular meals (predictable glucose) consistent sleep/wake times (hormonal entrainment) resistance training (muscle as a metabolic sink) daily walking (lymphatic + mitochondrial stimulus) and remove"
X Link 2026-01-09T19:04Z [---] followers, [---] engagements

"What youre describing is a real blind spot in conventional cardiology but its worth tightening the frame so it stays accurate and useful rather than swinging to the opposite extreme. A few key points Id add from clinical practice: Atherosclerosis is an inflammatorymetabolic disease first not a simple cholesterol storage disorder. Insulin resistance hyperglycaemia hypertension visceral adiposity sleep disruption and chronic stress all damage the endothelium. LDL then accumulates at the site of injury. Its a participant not the prime instigator. Statins lower LDL which reduces risk in people"
X Link 2026-01-09T23:48Z [---] followers, [--] engagements

"This is genuinely interesting work - but its important to place it in the right clinical frame. What this study supports is not that heart attacks are caused by bacteria instead of cholesterol but that atherosclerosis is a complex inflammatory disease in which infection can act as a trigger particularly for plaque rupture. A few key clarifications from a clinical perspective: Cholesterol-rich plaques still have to be there first. Bacterial biofilms dont create plaques out of thin air - they appear to colonise existing atherosclerotic plaque. The bacteria identified (e.g. viridans"
X Link 2026-01-10T17:49Z [----] followers, [----] engagements

"Absolutely. And what people often miss is when that chance quietly closes. In clinic the real regret isnt cosmetic decline - its lost capacity: joints that no longer tolerate load muscle mass thats hard to regain after [--] insulin resistance that calcifies into chronic disease sleep debt and stress biology that reshape the brain Your 30s and 40s are when the trajectory is set. After that youre mostly managing momentum. The body is remarkably forgiving early on - which is why neglect feels consequence-free. But it keeps a ledger. Movement strength sleep metabolic health and inflammation control"
X Link 2026-01-11T10:25Z [---] followers, [--] engagements

"Theres a grain of truth here but it needs tightening. Skin and hair are early reporters of internal physiology - but theyre signals not diagnoses. Early greying dark circles acne chapped lips etc usually reflect a convergence of factors: Chronic sympathetic overdrive (stress / poor sleep / circadian disruption) Mitochondrial energy shortfall Oxidative stress outpacing repair Micronutrient insufficiency plus impaired utilisation (thyroid gut liver) In practice I see far more functional bottlenecks than single deficiencies: Adequate intake poor absorption Normal labs poor tissue delivery Normal"
X Link 2026-01-11T14:09Z [---] followers, [----] engagements

"This is one of the most misunderstood feedback loops in physiology. Chronic fatigue is rarely an energy deficit - its an energy delivery problem. Inactivity down-regulates mitochondrial function reduces insulin sensitivity and blunts autonomic flexibility. The result is plenty of fuel on board but poor ability to access it. Gentle but consistent movement flips that switch: muscle contraction improves glucose uptake independent of insulin increases mitochondrial biogenesis and raises baseline ATP production. Within days people notice steadier energy - not because theyre resting more but"
X Link 2026-01-12T23:30Z [---] followers, [--] engagements

"Whats striking about that list isnt just the movement - its the mix of physiology and behaviour. The sports linked with the biggest longevity gains combine: Intermittent high intensity (sprints bursts direction changes) Coordination and reaction time (cognitive load) Upper + lower body engagement Social interaction (a massively under-appreciated longevity factor) Tennis and badminton in particular stress the heart and the brain while embedding regular social contact and purpose - a powerful anti-inflammatory and anti-depressive cocktail. In practice I see the longest-living healthiest"
X Link 2026-01-12T23:39Z [---] followers, [--] engagements

"That distinction matters clinically. Your circadian system isnt waiting for sunshine - its reading daylight intensity and spectrum. Even on overcast days outdoor daylight delivers [-----] more lux than indoor lighting and provides the blue-enriched wavelengths that activate melanopsin in the retina. That single morning signal: Anchors the cortisol awakening response Suppresses residual melatonin Improves insulin sensitivity and appetite timing Sets sleep quality [----] hours later In practice when people miss morning daylight (not sun) everything downstream drifts - energy mood glucose control"
X Link 2026-01-12T23:43Z [---] followers, [--] engagements

"This is one of those findings that sounds apocalyptic but actually needs careful interpretation - especially clinically. A few grounding points from practice and physiology: Exposure absorption. Ingested microplastics are not automatically systemically absorbed. The majority appear to pass through the gut and translocation rates depend on particle size shape surface chemistry gut integrity and bile flow. A leaky inflamed gut likely matters far more than raw intake numbers. Dose is driven by volume eaten not healthfulness. Fruits vegetables and grains dominate intake because they dominate mass"
X Link 2026-01-14T12:06Z [---] followers, [---] engagements

"This maps surprisingly well to what we see neurobiologically and clinically. Early on (first few weeks) habits are mostly willpower + novelty - high cognitive load lots of friction. By [---] weeks the behaviour starts shifting from the prefrontal cortex to basal ganglia circuits which is why it begins to feel more automatic and less effortful. The [---] month window is where most people either: relapse (because life stress tests the system) or consolidate (because the habit survives disruption) Whats often missed in health change is that identity follows physiology. Once sleep improves insulin"
X Link 2026-01-15T23:18Z [---] followers, [--] engagements

"Clinically this lands because evening exhaustion is rarely a willpower problem - its a nervous system and circadian problem. After a full workday decision fatigue + sympathetic overdrive make the brain default to low-energy behaviours (scrolling snacking numbing). That feels like rest but it doesnt restore ATP dopamine tone or parasympathetic balance. A few patterns I see repeatedly in practice: People who move lightly after work (walk short lift mobility) often feel more energy not less - muscle contraction improves insulin sensitivity and cerebral blood flow. A clear work is over ritual"
X Link 2026-01-15T23:39Z [---] followers, 12.6K engagements

"Decision quality deteriorates when cognitive space shrinks. Under time pressure or mental crowding the brain defaults to habit or avoidance rather than thoughtful choice. This is not poor judgement - its constrained processing. Creating space - temporal emotional or cognitive - improves decisions more reliably than trying harder. The brain thinks best when it has room to breathe. #Cognition #DecisionMaking #BrainHealth https://twitter.com/i/web/status/2012258543164919946 https://twitter.com/i/web/status/2012258543164919946"
X Link 2026-01-16T20:19Z [----] followers, [---] engagements

"The quote is crude but the physiology behind the image is very real. From a clinical perspective movement isnt just about muscles or calories its a neurological stimulus. Even light walking increases cerebral blood flow nitric oxide signalling lymphatic drainage and afferent input from joints and muscles back to the brain. That sensory feedback literally changes cortical activation patterns within minutes. I see this daily with patients who report: clearer thinking after a short walk improved mood and creativity reduced pain sensitivity better glucose regulation Prolonged sitting does the"
X Link 2026-01-16T21:43Z [---] followers, [---] engagements

"Theres a real biological signal here but it needs careful framing. Many cancers do show glucose dependency (the Warburg effect) and lowering glycaemic load can reduce insulin and IGF-1 signalling which are growth-promoting pathways. Thats why metabolic therapies like ketogenic or low-glycaemic diets are being actively studied as adjuncts in oncology particularly alongside chemo radiotherapy or immunotherapy. Clinically the nuance matters: Not all tumours are equally glucose-dependent Some cancers can adapt and utilise glutamine fatty acids or ketones Cachexia weight loss and sarcopenia are"
X Link 2026-01-17T15:10Z [---] followers, 10.1K engagements

"One subtle marker of good cognition is how easily the brain releases completed thoughts. When cognitive load is high thoughts linger unnecessarily creating background noise that feels like brain fog. Restoring the ability to close mental loops - finish release move on - is deeply protective. Quiet minds are efficient minds. #BrainHealth #CognitiveWellbeing #Longevity https://twitter.com/i/web/status/2012892140951548257 https://twitter.com/i/web/status/2012892140951548257"
X Link 2026-01-18T14:17Z [---] followers, [---] engagements

"This is the distinction most people miss. Subcutaneous fat is largely a storage issue. Ectopic fat (liver muscle myocardium pancreas) is a metabolic toxicity issue. Clinically the patients I worry about most arent always the ones with the biggest waistlines theyre the ones with: Fatty liver despite a normal BMI Rising fasting insulin with modest weight gain Loss of muscle insulin sensitivity (early sarcopenia) Elevated triglycerides and low HDL Once fat spills out of safe storage and into organs it disrupts mitochondrial function impairs insulin signalling drives inflammation and accelerates"
X Link 2026-01-18T14:31Z [---] followers, [---] engagements

"Theres a useful signal here but it needs tightening to avoid oversimplification. Hair follicles are among the most metabolically active tissues in the body so they are extremely sensitive to oxygen delivery iron availability and mitochondrial energy. A normal haemoglobin can still coexist with functional iron deficiency or impaired utilisation. A few key clinical nuances I see repeatedly: Ferritin matters more than haemoglobin for hair. Many women shed at ferritin [----] ng/mL even with Hb in range. For regrowth [-----] ng/mL is often needed. Inflammation blocks iron use. Elevated CRP or hepcidin"
X Link 2026-01-18T21:12Z [----] followers, [---] engagements

"This is broadly true but the nuance that matters clinically is rate of decline not just peak fitness. What protects people at [--] isnt simply having been elite at [--] but having: Preserved muscle quality (strength per unit mass) Maintained insulin sensitivity Avoided chronic inflammation Kept connective tissue and mitochondria healthy I see plenty of former high-performers who trained hard in their 30s then stopped accumulated metabolic damage and fell off a cliff in their 50s. Conversely I also see people who were very average at [--] but who: Started resistance training Prioritised protein"
X Link 2026-01-19T01:59Z [----] followers, [---] engagements

"This is a classic example of how mechanism without context becomes misinformation. First an important correction: sweet potatoes are not nightshades. Theyre Ipomoea batatas (morning glory family) not Solanum. They do not contain solanine or classic nightshade alkaloids. White potatoes are the nightshades not sweet potatoes. Now to the real clinical issues - because sweet potatoes still arent a universal health food. Key clarifications: Oxalates Yes sweet potatoes contain them. But kidney stone risk is driven far more by low hydration low dietary calcium high sodium insulin resistance and gut"
X Link 2026-01-19T02:28Z [----] followers, [---] engagements

"One of the earliest changes people notice isnt memory loss-its reduced mental endurance. The brain still works but sustained thinking feels harder to maintain especially later in the day. This reflects a narrowing of cognitive bandwidth rather than loss of ability. When endurance drops people conserve effort by simplifying decisions and avoiding complexity. Recognising this early helps prevent mislabelling it as decline rather than a signal to adjust load. #BrainHealth #Cognition"
X Link 2026-01-20T02:29Z [----] followers, [--] engagements

"This exchange captures a very real tension in modern medicine - and its not about denial of risk its about model mismatch. LDL isnt irrelevant. But LDL in isolation is a blunt tool especially when the rest of the metabolic context has clearly improved. A few clinical realities worth naming: LDL is a transport particle not a toxin. Its atherogenicity depends on context: insulin resistance inflammation oxidative stress endothelial injury and particle number/retention - not just concentration. When triglycerides fall HDL rises CRP normalises insulin sensitivity improves and LDL particle size"
X Link 2026-01-20T02:55Z [----] followers, [---] engagements

"Theres real biology behind this. Reading isnt passive entertainment - its active neural training. It forces sustained attention working memory symbolic processing and internal narrative construction. That combination uniquely exercises the prefrontal cortex temporal language networks and the default mode network - the same systems that underpin reasoning empathy and imagination. Clinically people who stop reading often dont just know less - they think more shallowly. Vocabulary shrinks nuance collapses and ideas become reactive rather than reflective. We see the opposite in lifelong readers:"
X Link 2026-01-22T00:34Z [----] followers, [---] engagements

"This is psychologically sharp - and theres solid biology underneath it. Open loops keep the brain in a low-grade threat-monitoring state. The nervous system treats unresolved social emotional and decision-based tasks as unfinished threats so the stress response never fully switches off. Cortisol stays elevated the prefrontal cortex keeps checking and mental energy leaks all day. Clinically I see this present as: persistent fatigue despite adequate sleep brain fog without metabolic disease feeling wired but tired difficulty relaxing even on rest days Its not laziness or poor resilience - its"
X Link 2026-01-22T00:48Z [----] followers, [--] engagements

"This isnt really about dentistry - its about how people struggle with loss fear and trade-offs. Clinically a chronically infected tooth isnt a local issue. Its a persistent source of inflammation and bacterial load that can worsen metabolic health cardiovascular risk and systemic immune stress. Antibiotics dont fix necrotic tissue and waiting doesnt pause disease - it lets it progress. What patients often mean isnt I dont want treatment but I dont want to accept the consequences. The real decision tree is simple: Remove the source of infection Then choose how to manage the space (implant"
X Link 2026-01-22T00:54Z [----] followers, [---] engagements

"Theres a lot of clinical truth in this and its less about the food itself and more about decision fatigue and metabolic noise. When patients eat the same simple meals day-to-day a few things reliably happen: Calorie intake stabilises without tracking Blood glucose variability drops Hunger hormones calm down Stress around food decisions disappears Consistency removes friction. The nervous system likes predictability and so does metabolism. That said I frame this as a phase not a religion. Monotony works brilliantly for fat loss because it creates a controlled environment. Once someone reaches"
X Link 2026-01-23T16:28Z [----] followers, [---] engagements

"Absolutely. Clinically the biggest benefit of the gym isnt the workout stimulus its the signal you send your nervous system. Showing up when motivation is low reinforces self-efficacy and stress resilience. That consistency lowers baseline cortisol over time improves insulin sensitivity and makes future healthy decisions easier. In contrast waiting to feel ready keeps people stuck in a reward-dependent loop. Some of the best metabolic and mental health gains I see come from people who train at 6070% effort but do it reliably. The body adapts to patterns not heroic days. Discipline isnt"
X Link 2026-01-23T16:30Z [----] followers, [--] engagements

"This is such an important point and its one I see play out clinically all the time. Just eat whole foods is biochemically correct but behaviourally incomplete. Nutrition doesnt fail because people dont understand what a vegetable is. It fails because advice ignores the execution layer. In practice dietary change succeeds or collapses based on: time bandwidth cognitive load food skills and confidence kitchen infrastructure family dynamics and unequal labour distribution financial and spoilage risk A bell pepper isnt a meal. A guideline isnt a system. When we actually get results its because we"
X Link 2026-01-23T20:36Z [----] followers, [----] engagements

"This sits in a grey zone that deserves nuance rather than headlines. There is a legitimate well-described concept of focal infection and chronic low-grade inflammation - and dentistry isnt exempt from that conversation. Poorly treated oral infections periodontal disease and chronic apical inflammation clearly increase systemic inflammatory burden and cardiovascular risk. That part is solid. Where things go off the rails is jumping from: chronic oral infection can contribute to systemic disease to root canals cause cancer. The evidence simply doesnt support that leap. In modern dentistry a"
X Link 2026-01-23T21:09Z [----] followers, [----] engagements

"This lines up exactly with what we see clinically - but the most important nuance is that this decline is not inevitable. Yes VO max and muscle power peak early. But the 12% per year loss is largely a disuse phenomenon not a biological mandate. The curves look very different in people who continue to train with intent. Two key points often missed: Muscle power (strength speed) declines faster than strength alone which is why falls frailty and loss of independence accelerate unless people train explosively not just stay active. Aerobic capacity is remarkably plastic even later in life."
X Link 2026-01-24T03:07Z [----] followers, [---] engagements

"Speaking as an Emergency Medicine consultant this is exactly the distinction most people arent taught. The ED is built for undifferentiated potentially life-threatening illness. Once you cross that threshold we are obligated to rule out worst-case scenarios sepsis pyelonephritis PE ACS - even if the probability is low. That means broad bloods imaging monitoring IV access and yes eye-watering costs. Thats not overkill; its defensive protocol-driven emergency care. For a stable uncomplicated UTI that level of care is usually unnecessary. Urgent care or telehealth is often entirely appropriate"
X Link 2026-01-25T00:10Z [----] followers, [---] engagements

"Theres a kernel of truth here but its also a great example of how nutrition shortcuts can mislead. Milk + orange juice will cover a surprising amount of calories calcium potassium carbs vitamin C B12 riboflavin and even some protein. From a purely micronutrient spreadsheet perspective it looks almost complete. But clinically a few big gaps show up fast: No iron zinc iodine selenium in meaningful amounts Very little omega-3 (DHA/EPA) No choline which is critical for liver and brain health No fiber or polyphenols for gut signaling And for many adults that much lactose + sugar = insulin spikes"
X Link 2026-01-25T01:07Z [----] followers, [----] engagements

"From a clinical perspective this aisle isnt here because people are stupid - its here because it solves a short-term problem while quietly creating a long-term one. These bars are engineered to be portable palatable shelf-stable and healthy-coded - not to nourish. They keep blood sugar oscillating just enough to feel functional but never stable enough to restore metabolic health. In practice I see this aisle most often in people who are: under-eating real meals over-scheduled chronically stressed relying on convenience instead of satiety Whole food doesnt need branding claims or protein grams"
X Link 2026-01-25T01:58Z [----] followers, [--] engagements

"This mirrors what we see clinically all the time. The biggest mortality dividend comes from going from sedentary to something. The curve is steep early then flattens. You dont need to optimize exercise to get most of the benefit - you need to cross the inactivity threshold. Two practical takeaways I emphasise with patients: Consistency beats intensity. Daily walking light resistance work stairs - boring repeatable inputs move the needle most. Muscle matters. The weight-training curve may look modest here but preserving lean mass is what protects glucose control bone density falls risk and"
X Link 2026-01-25T02:11Z [----] followers, [---] engagements

"As someone who sees both ends of the spectrum clinically I agree with the principle but would refine the framing. Blanket full-body check-ups often create noise false positives anxiety and cascades of unnecessary follow-up. More testing better prevention. But equally minimalist screening misses risk in the people who need it most. What actually works in practice is stratified prevention: Right test Right person Right time Right context A 30-year-old endurance athlete doesnt need the same work-up as a 45-year-old with visceral adiposity insulin resistance poor sleep and a family history of"
X Link 2026-01-25T19:23Z [----] followers, [----] engagements

"Theyre a good example of how context matters more than labels like superfood. Watermelon seeds are indeed nutrient-dense by weight - rich in magnesium zinc copper some protein and polyunsaturated fats. In cultures where seeds are roasted ground or eaten intentionally they can meaningfully contribute minerals. But clinically two nuances often get missed: Most people swallow very few seeds whole and intact seeds arent well digested - bioavailability is low unless theyre chewed roasted or ground. For some patients (IBS SIBO gut inflammation) a high seed load can aggravate symptoms despite the"
X Link 2026-01-25T19:33Z [----] followers, [---] engagements

"This kind of work is exciting because it bridges two truths we often talk about in practice: 1.Our biology is light-responsive - not just for vision but for mitochondrial signalling circadian rhythm and cellular redox state. 2.Most modern environments are straitjackets of artificial light that suppress key pathways (melatonin nitric oxide mitochondrial dynamics) that evolved under broad spectrum sunlight. Infrared isnt a random biohack. Infrared wavelengths penetrate tissues more deeply and have been shown experimentally to: increase mitochondrial membrane potential improve ATP production"
X Link 2026-01-25T22:46Z [----] followers, [---] engagements

"Biohack isnt a term I use lightly or ideologically. Strip away the buzzword and it simply means modifying inputs to influence physiology. Thats been medicine for centuries - we just used to call it environmental exposure. And the signal analogy isnt philosophical fluff. Biology runs on it. Light is a zeitgeber - a time-setting signal - detected by specialised retinal photoreceptors that talk directly to the hypothalamus mitochondria endocrine system and immune function. If those pathways are intact the signal is received. If theyre disrupted (poor sleep metabolic disease chronic inflammation)"
X Link 2026-01-26T01:42Z [----] followers, [--] engagements

"What the POUNDS LOST data highlights isnt that one macronutrient ratio is inherently superior - its that caloric deficit + metabolic context drive change not dogma about fat vs carbs vs protein. A few insights I see repeatedly in practice that help interpret these trials: [--]. Fat mass loss tracks with energy balance but where the body loses fat matters. Visceral adipose tissue and hepatic fat are the true drivers of metabolic risk. These tend to respond most when insulin sensitivity improves - regardless of whether that comes from higher protein lower carbs or balanced diets. [--]. Protein isnt"
X Link 2026-01-26T02:11Z [----] followers, [---] engagements

"Theres a balance here thats worth naming. Wearables are useful training wheels not a replacement for interoception. They can teach patterns early on but when people stay dependent on numbers they often lose trust in their own physiology. In clinic I see it all the time: People feel fine but panic because HRV dipped People feel exhausted but push anyway because the app says recovered Sleep becomes something to perform rather than experience Your nervous system doesnt speak in metrics - it speaks in appetite mood energy libido warmth recovery and motivation. Those signals are higher-bandwidth"
X Link 2026-01-24T18:42Z [----] followers, [---] engagements

"A simple but powerful nudge. What this kind of visual does well clinically isnt biohacking - its restoring time perspective. When people can see finitude behaviour changes upstream: sleep improves boundaries firm up trivial stressors lose their grip. In practice the patients who do best long-term are the ones who stop asking How do I optimise everything and start asking What actually matters if time is limited That shift alone lowers cortisol improves decision-making and paradoxically leads to better health behaviours without force. Sometimes the most therapeutic intervention isnt another"
X Link 2026-01-25T18:28Z [----] followers, [----] engagements

"The striking thing here isnt the number - its what the steps represent biologically. Regular walking isnt just calorie burn. Its: Continuous low-grade muscle contraction glucose uptake without insulin Rhythmic loading of bones preserves bone density Repeated nitric oxide release vascular health Lymphatic flow immune and inflammatory regulation Gentle parasympathetic activation lower cortisol In clinic people who simply make daily movement non-negotiable often see improvements in blood sugar BP sleep mood and cognition before we touch anything more advanced. You dont need extremes. You need"
X Link 2026-01-26T01:53Z [----] followers, [---] engagements

"This is a great example of where mechanism + context matters. The pomegranate data is genuinely interesting - especially the effects on LDL oxidation PON-1 activity and carotid IMT which speak to oxidative stress and endothelial biology rather than simple cholesterol lowering. Thats a very different target to most drugs and clinically relevant. But a few important caveats from practice: These studies were small selected cohorts with established atherosclerosis not healthy 30-year-olds. The benefit appears driven by polyphenols not the sugar load. Commercial pomegranate juice can deliver 3040g"
X Link 2026-01-28T08:38Z [----] followers, [---] engagements

"Decision difficulty isnt always about indecision. Often its about compressed decision space - too many variables competing at once. When decision space expands again choices feel lighter even if the options havent changed. Supporting this expansion is often more effective than simplifying life down to basics. #Cognition #BrainFunction https://twitter.com/i/web/status/2017307584047550821 https://twitter.com/i/web/status/2017307584047550821"
X Link 2026-01-30T18:43Z [----] followers, [--] engagements

"This aligns with what many of us see clinically with a few important nuances worth adding. Vitamin D here is likely acting less as a boost and more as a permissive signal for immune competence. Below a certain threshold innate immunity (cathelicidin defensins macrophage function) simply doesnt work properly. Once you correct deficiency risk drops quickly. Beyond sufficiency returns flatten. Two practical points from practice: Baseline matters the biggest gains are consistently in those who are deficient. Blanket high-dose supplementation in already replete individuals delivers far smaller"
X Link 2026-01-31T07:21Z [----] followers, [---] engagements

"Theres some truth in this - but not for the reason most people think. Being lean without a GLP-1 increasingly signals that your metabolic regulation is intact: appetite signalling insulin sensitivity gutbrain communication sleep and stress hormones are all doing their jobs. Thats becoming rarer in an obesogenic environment engineered to overwhelm those systems. Clinically what I see isnt willpower vs drugs - its physiology vs dysfunction. GLP-1s are powerful tools for people whose signalling is broken. But if you can stay lean without pharmacologic appetite suppression it usually means:"
X Link 2026-01-31T08:30Z [----] followers, [---] engagements

"This is genuinely interesting work - but its being oversold if framed as heart attacks are caused by bacteria. A more accurate clinical interpretation is this: Atherosclerosis still sets the stage. Plaque formation is a decades-long process driven by ApoB-containing lipoproteins endothelial dysfunction metabolic inflammation smoking blood pressure etc. Biofilms dont create plaques from nothing. Bacteria may be a plaque destabiliser not the primary cause. The idea that dormant microbial biofilms (oral streptococci Chlamydia pneumoniae others) can sit within established plaques and become"
X Link 2026-01-31T19:23Z [----] followers, [---] engagements

"Heres the harsh truth I end up sharing in clinic with my patients - gently but honestly: Weight loss isnt hard because you lack discipline. Its hard because your biology is fighting to keep you the same. Your brain is wired to defend body fat not to reward thinness. If youve been metabolically unhealthy chronically stressed sleep-deprived insulin resistant inflamed or hormonally dysregulated willpower alone is irrelevant. A few uncomfortable realities: You cant out-exercise poor sleep chronic stress or blood sugar chaos. If your environment keeps spiking dopamine and insulin fat loss will"
X Link 2026-01-31T19:30Z [----] followers, [---] engagements

"A subtle but common shift: people become less comfortable with open-ended situations. They want clearer answers firmer plans fewer loose ends. Clinically this reflects reduced cognitive slack. Ambiguity requires holding multiple possibilities at once. When bandwidth narrows certainty feels safer - not because someone is rigid but because the brain is conserving effort. https://twitter.com/i/web/status/2018674109375242353 https://twitter.com/i/web/status/2018674109375242353"
X Link 2026-02-03T13:13Z [----] followers, [--] engagements

"Thats a solid start. Id add a few things that matter clinically but often get missed because theyre less sexy than gear: Natural light timing brightness alone morning outdoor light (even [---] mins) does more for circadian alignment than a 10000-lux lamp at random times. Use the lamp strategically not all day. CO monitoring cognitive performance drops surprisingly fast once indoor CO creeps above [----] ppm. Plants help a bit ventilation helps a lot. Micro-movement prompts not just a standing desk but cues to change posture every [----] minutes. Static standing isnt much better than static sitting."
X Link 2026-02-04T07:38Z [----] followers, [--] engagements

"When people mistake fatigue for decline 1/ Many patients say I can still thinkbut not for long"
X Link 2026-02-05T08:35Z [----] followers, [---] engagements

"The EMF levels from cell phones are non-ionizing radiation - orders of magnitude too weak to cause DNA damage or the cascade of effects listed here. The WHO's International EMF Project and multiple systematic reviews have found no consistent evidence that low-level EMF exposure from phones causes these outcomes. That said sleeping next to your phone CAN disrupt sleep - just not because of EMFs. Late-night scrolling notification alerts and blue light exposure are the real culprits. The right advice (phone away from bed) for the wrong reason. https://twitter.com/i/web/status/2020546001296339118"
X Link 2026-02-08T17:11Z [----] followers, [--] engagements

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