@AKoutnik Andrew Koutnik, Ph.D.

Andrew Koutnik, Ph.D. posts on X about health, this is, science, weight loss the most. They currently have [-----] followers and [---] posts still getting attention that total [------] engagements in the last [--] hours.

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Mentions: [--] #

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CreatorRank: [---------] #

Social Influence

Social category influence technology brands countries finance social networks stocks

Social topic influence health, this is, science, weight loss, if you, strong, comments, instead of, lack of, work for

Top accounts mentioned or mentioned by @proftimnoakes @dominicdagosti2 @nicknorwitz @benbikmanphd @dikemandave @doctortro @janellison @chrispalmermd @loreofrunning1 @bholmer @charbrisc @exfatloss @ketocarnivore @leoabstract @raphaels7 @sudas1891 @carnivoreaugust @zbitter @joseantoniophd @drnadolsky

Top assets mentioned GrokCoin (GROKCOIN) Spotify Technology (SPOT) BETA Technologies, Inc. (BETA) GLP1 (GLP1) New York Times Co. (NYT)

Top Social Posts

Top posts by engagements in the last [--] hours

"Credit @AnnalijnConklin & her team for illustrating an incredibly important gap. This study was Canada-based which is a country which has been more progressive on these initiatives. Trying to address these gaps to support patients and providers. 3/3"
X Link 2022-11-25T15:06Z [----] followers, [--] engagements

"Keto-adaptation: Glycogen* (1/3): See attached image. -Webster et al. included* -3/4 attempted weight stable condition (Miller et al. excluded). -All similar techniques. -Across studies comparison requires assumptions but it is the data we have. https://pubmed.ncbi.nlm.nih.gov/26918583/ Keto-adaptation time: Glycogen load & resynthesis -4weeks + isocaloric: 46% drop (https://t.co/QuoyOKoMrF) [---] weeks + weight loss: 14% drop (https://t.co/U8MHIDfAKG) -9-20month + weight stable: No difference (https://t.co/YVezNcmmDd) -Work needed on these temporal change. 7/n"
X Link 2023-03-01T15:17Z [----] followers, [----] engagements

"2days in.😳 Didn't even drop it @novonordisk"
X Link 2023-04-22T20:28Z [----] followers, [---] engagements

"Type-1 Diabetes @RogueFitness Echo [--] minutes: [----] miles 2nd time on it. Improving. Does anyone know some reference ranges on this machine"
X Link 2023-07-11T19:14Z [----] followers, [---] engagements

"@erogul1 We are now on 5-7 generation tech in CGM which actually take real biological values. It took years of getting to the point where they are now. I suspect a wearable will take even longer and may never reach the same accuracy but I hope I'm wrong"
X Link 2023-07-13T04:26Z [----] followers, [--] engagements

"Type-1 Diabetes Closed loop. Time to give it a shot"
X Link 2023-08-11T16:03Z [----] followers, 10.1K engagements

"Incredible findings but should we be completely surprised GLP1 prolong honeymoon in T1D -This drug reliably food intake -They reported carb restriction. -Adult patients Prior work (which was maligned) shows beta cell restoration in therapies that model reduced food intake treatments: Prior case reports carb restriction extend honeymoon T1D adults tend to have slower beta cell decline. Others thoughts @EricTopol @DanielJDrucker @BenBikmanPhD @ChrisPalmerMD @JimJohnsonSci"
X Link 2023-09-08T16:53Z [----] followers, [----] engagements

"@AmerAcadPeds clinical guidance on low-carb diets in children with type [--] diabetes 🔥 topic 🔍T1D recommendations for kids -LCD/VLCD not recommended w/o medical oversight -Mediterranean & US Dietary Guidelines are healthy options -Etc. See 👇"
X Link 2023-09-21T14:19Z [----] followers, [---] engagements

"#1 T1D Conclusion) Low-carb diets are not recommended for children & adolescents with type [--] diabetes except under close supervision utilizing safety guidelines. Why this recommendation a. Medical Supervision b. Lack of Evidence b. Concerns c. Other 👇"
X Link 2023-09-21T14:19Z [----] followers, [--] engagements

"1a. Medical Oversight Medical oversight recommended for LCD/VLCD in T1D Kids.✅YES .but there is a problem.66% of dieticians don't feel knowledgeable or support to implement LCD/VLCD. Why No Evidence-Based Guidelines Lack of Evidence👇"
X Link 2023-09-21T14:19Z [----] followers, [--] engagements

"Type [--] Diabetes Lower Body RE (building back strength) Squat: 295x2 335x2 295x3 295x5 Deadlift (Block): 405x5 425x5 385x7 RFESS (3xMax) 15min 🏃♂ Meal 1hr Prior (Protein+Fat Based) Stable BG"
X Link 2023-10-22T15:59Z [----] followers, [---] engagements

"Ketogenic Diet has diverse effects on thyroid function biomarkers compared to high carbohydrate diets. Question is will this will be attached to real clinical changes. Is so what Interesting area of research. Prior research was speculative"
X Link 2023-11-25T16:11Z [----] followers, [----] engagements

"College Football Playoffs I have conducted a detailed AI driven analysis of potential playoff participants. Upon conclusion FSU is the only team who should be guaranteed a final [--] spot. Publication in Cell soon. Reach out to PI for algorithm code post-publication"
X Link 2023-11-25T19:56Z [----] followers, [---] engagements

"Non-nutritive sweeteners improve weight compared to control (water) IN HUMANS in a year-long RCT. Interesting.since some will interpret this that NNSwater. At the very least they appear to support weight loss"
X Link 2023-11-28T00:19Z [----] followers, [---] engagements

"Identical Twins [--] identical twins consuming either a plant based or omnivore (plants and meat) diet. Plant based: -Lower BMI -Lower Fasting Insulin -Lower LDL Not often you see a study like this in numerous twins"
X Link 2023-11-30T22:26Z [----] followers, 11K engagements

"Wow.left Florida State out of the #CollegeFootballPlayoff & Alabama jumped [--] points.unreal. Extremely reactionary to one week of play"
X Link 2023-12-03T17:32Z [----] followers, [----] engagements

""X: Grok Please Roast Me" 🤣🤣🤣🤣"
X Link 2024-01-02T00:31Z [----] followers, [---] engagements

"Reasons for hospitalization in youth with type [--] diabetes 2010-2019 (Australia) Type-1 Diabetes compared to controls: -Infection: 6-55% relative risk -Mental Health: 4-10% relative risk -Eye (Cataracts): 35% relative risk -Digestive: 6-13% relative risk -Skin: 3-7% relative risk -Musculoskeletal: 4% relative risk -Genitourinary: 3-13% relative risk -Injury & poisoning (adverse effects of hormones): 7-195% relative risk"
X Link 2024-01-19T12:31Z [--] followers, [---] engagements

"Type [--] Diabetes Remission in 56% on very low CALORIE diet over [--] month Very impressive https://diabetesjournals.org/care/article/47/1/66/153542/Intensive-Lifestyle-Intervention-for-Remission-of https://diabetesjournals.org/care/article/47/1/66/153542/Intensive-Lifestyle-Intervention-for-Remission-of"
X Link 2024-01-20T22:52Z [----] followers, 11.3K engagements

"New study from @pl_valenzuela on EXOGENOUS KETONES in patients who cannot utilize muscle glycogen (McArdle) Study suggests muscle glycogen may have a role in the performance effect of exogenous ketones Love unique studies like this which really give important nuance to how substrates affect physiology. For context for context see our prior review on the performance role for exogenous ketones:"
X Link 2024-01-31T13:51Z [----] followers, [----] engagements

"@ZKForTre but you can compare to baseline. @BenBikmanPhD has a point. Similar findings here (Fig 7c) from @Gonzalez_JT @AaronHengiswith with just VLCD meal at baseline to post prandial timepoint if you compare it to baseline (even this meals contain protein which in and of itself will increase glucose levels)"
X Link 2024-02-16T20:23Z [----] followers, [---] engagements

"Completed [--] hours 500kcal/day R-BHB [---] - 1.4mM-2.2mM Insulin 0.3IU/kg - 0.1IU/kg Interesting. [--] hours in lower body resistance exercise induced glycogenolysis up to 190mg/dL. .normally I would never see this. Suspect this was due to RPE from caloric deficit. Despite continually VL carb diet & 72h VL calorie deficit glucagon-induce hepatic glucose release was still intact. 🤔 #type1diabetes"
X Link 2024-02-27T13:19Z [----] followers, [----] engagements

"Hypoglycemia & Cardiac Arrests ("dead in bed" syndrome) Hypoglycemia can prolong cardiac Q-T interval (arrhythmia). HOWEVER.hypoglycemic stress is transient. .it is believed that it is the accumulated CVD dysfunction (endothelial dysfunction) from chronic hyperglycemia that places the cardiovascular system at elevated risk from the acute "stress" of hypoglycemia. Establishing optimal glycemic control early upon diagnosis is STRONGLY encouraged as signs of endothelial dysfunction are observed within 4years of diagnosis. See: -Hypoglycemia Diabetes and Cardiovascular Disease - PMC -Vascular"
X Link 2024-03-04T13:45Z [----] followers, [----] engagements

"Ketogenic diet has positive association with mental and emotional well-being in the general population 🍽 - 🧠 N=361. Samples social media. Interesting as interest emerges on KD and mental health. Will be interesting to see these develop into RCTs"
X Link 2024-03-09T21:20Z [----] followers, [----] engagements

"Backlash from type [--] diabetes community on general population access to CGM ALOT has been learned about glucose from the T1D community using CGMs FIRST. That was its origin. I don't think we should be prevent access to others who want this data also"
X Link 2024-03-13T17:34Z [----] followers, [----] engagements

"🚨 @AmDiabetesAssn Keto Diets in Diabetes: Evidence in Type [--] & Type [--] Diabetes I will be presenting the EVIDENCE on carbohydrate restriction in diabetes in ADA Nutrition Webinar (FREE). 👇 Please SHARE for all to attend https://professionaleducation.diabetes.org/Public/Catalog/Details.aspxid=SsLSjMuSB2%2fi6z0ETIFiog%3d%3d&returnurl=%2fUsers%2fUserOnlineCourse.aspx%3fLearningActivityID%3dSsLSjMuSB2%252fi6z0ETIFiog%253d%253d"
X Link 2024-03-29T18:45Z [----] followers, 31.1K engagements

"@PatsyDiabetes can you confirm @grok analysis"
X Link 2024-04-15T00:52Z [----] followers, [---] engagements

"🚨Please share your lived experience with Type [--] Diabetes & Food (5-10 minutes survey): We have heard from [---] people internationally but we need your help Please share @AnnalijnConklin @JimJohnsonSci @JDRF_Canada @JDRF https://ubc.ca1.qualtrics.com/jfe/form/SV_esbnV693mudhdPM https://ubc.ca1.qualtrics.com/jfe/form/SV_esbnV693mudhdPM"
X Link 2024-04-23T23:46Z [----] followers, 63.3K engagements

"Creditable scientists/clinicians have to put out high-quality content to contend with this. Accepting social media is here is stay is step one. Incentivizing creditable sources to partake in information dissemination seems like an important step. Maybe there is another way I just don't see it"
X Link 2024-05-07T20:26Z [----] followers, [---] engagements

"@KetoCounselor @AnnalijnConklin @JimJohnsonSci @JDRF_Canada @JDRF Don't have a LinkedIn. Probably should make one"
X Link 2024-05-12T14:21Z [----] followers, [--] engagements

"Type [--] Diabetes YOUTH & Obesity: 35.5% of T1D are overweight/obese at diagnosis .5 years later.52.8% overweight/obese. Alarming rise. https://www.endocrinepractice.org/article/S1530-891X(24)00511-1/abstract https://www.endocrinepractice.org/article/S1530-891X(24)00511-1/abstract https://www.endocrinepractice.org/article/S1530-891X(24)00511-1/abstract https://www.endocrinepractice.org/article/S1530-891X(24)00511-1/abstract"
X Link 2024-05-17T21:19Z [----] followers, [----] engagements

"Cardiovascular & Diabetes Mortality in T1D & T2D in Denmark from 2002-2020 -Analyses of predictive variables would've been interesting here (e.g. HbA1c trends over this period since they had them to define diabetes). https://www.sciencedirect.com/science/article/pii/S2666776224000759#fig1 https://www.sciencedirect.com/science/article/pii/S2666776224000759#fig1"
X Link 2024-05-20T14:01Z [----] followers, [---] engagements

"Twitter's description of Ozempic says that it is praised for its "effectiveness" (a clinical term) in managing type [--] diabetes. I am pretty sure it meant to say T2D.🫠 Excited to see the data on T1D as it comes. AI doesn't always get it right"
X Link 2024-05-30T22:39Z [----] followers, [---] engagements

"Novo Nordisks once-weekly experimental insulin denied FDA approval. Cited risk benefit (hypoglycemia) https://beyondtype1.org/novos-once-weekly-insulin-is-a-no-go-with-fda-advisory-panel/ https://beyondtype1.org/novos-once-weekly-insulin-is-a-no-go-with-fda-advisory-panel/"
X Link 2024-06-03T18:52Z [----] followers, [----] engagements

"I was asked yesterday what a standard meal does in Type [--] Diabetes. Self experiment. Fasted. Single meal (25% Total Calories): -55% Carbohydrates (brown rice) -21% Lipid (olive oil) -24% Protein (egg white protein) Peak BG: 373mg/dL. 3.5hours to come back down to normoglycemia. .AND despite high insulin sensitivity and automated insulin delivery system"
X Link 2024-06-04T16:49Z [----] followers, 71.3K engagements

"@JoseAntonioPhD & SportsScienceDudes asked about nutrition & T1D per my post below. See full discussion here: YouTube: Apple: Spotify: https://open.spotify.com/episode/1u6OE90EKqD5W8bDWBlevNsi=rTOGBS3MRb-JqTE48ti7vg&nd=1&dlsi=240e2858874f4af6 https://podcasts.apple.com/us/podcast/sports-science-dudes/id1670156526i=1000657779623 https://www.youtube.com/watchv=8gj3jMKEYio I was asked yesterday what a standard meal does in Type [--] Diabetes. Self experiment. Fasted. Single meal (25% Total Calories): -55% Carbohydrates (brown rice) -21% Lipid (olive oil) -24% Protein (egg white protein) Peak BG:"
X Link 2024-06-04T17:13Z [----] followers, [---] engagements

"I blended them together so there was no order effect. This was as controlled an experiment as possible. -Fasted -Rested -First meal (no multiple meal effect) -No physical activity confounders -Measured all ingredients. Blinded them together. Consumed within 10mins. -Insulin load prior to trial matched my typical daily IU/kg. Many other things were done to make this a real and repeatable nutritient-induced effect"
X Link 2024-06-04T18:22Z [----] followers, [----] engagements

"The graph didn't show my basal leading in but it was on. Some reason it didn't show but I have the data. My insulin and BG levels were consistent with my normal average leading into the experiment. Basal auto adjusted up. Bolus automatically administered based on CGM. No user bias on BG or insulin needs"
X Link 2024-06-04T19:06Z [----] followers, [----] engagements

"Late. Didn't want to. But I did. Happy Friday"
X Link 2024-06-15T05:17Z [----] followers, [---] engagements

""GLP1a faster weight loss is NOT better than slower more prolonged weight loss." Why: "Maintain adequate nutrients" "Ability to exercise" "We should be focused on health not just (rapid) weight (loss)." Brings into question about more potent GLP1a drugs. #ADA2024 @MichaelAlbertMD @DrNadolsky @DanielJDrucker thoughts"
X Link 2024-06-22T13:34Z [----] followers, [----] engagements

"T2D Remission -A Common Goal -Weight loss and it's maintenance appear to be important regulators #ADA2024"
X Link 2024-06-22T19:55Z [----] followers, [---] engagements

"Is Weight Loss Everything Nutrition & Lifestyle Are Missing Puzzle Pieces -Colleen Dawkins FNP-C RDN "Very low % of patients are referred to a dietician during GLP1a." Alot of tools tricks health & quality of life considerations during GLP1a (& maintenance). #ADA2024"
X Link 2024-06-22T20:06Z [----] followers, [---] engagements

"@mackinprof GLP1a versus VLCD Context: Very true for obesity. But type [--] diabetes OBESITY -Low Carb: (10%) -TRZ: (21%) T2D -Low Carb: (12%) -TRZ: (12%) I am sure as GLP1a becomes more potent we may see superiority in T2D but not so clear when looking at intensive approaches stacked with VLCD or GLP1a. Let me know if you see it differently https://www.nejm.org/doi/full/10.1056/NEJMoa2107519 https://pubmed.ncbi.nlm.nih.gov/29417495/ https://www.nejm.org/doi/full/10.1056/NEJMoa2206038 https://www.nejm.org/doi/full/10.1056/NEJMoa022207 https://www.nejm.org/doi/full/10.1056/NEJMoa2107519"
X Link 2024-07-01T15:32Z [----] followers, [---] engagements

"@CakeNutrition True .99.99% of people will never be Olympic athletes. .what happens if the general pop followed some Olympic athletes' calories and dietary strategies (carnivore aside) ⚖📈"
X Link 2024-07-27T16:14Z [----] followers, [----] engagements

"Patients push back against Novo Nordisk move to scrap an insulin product https://www.reuters.com/business/healthcare-pharmaceuticals/patients-push-back-against-novo-nordisk-move-scrap-an-insulin-product-2024-07-30/ https://www.reuters.com/business/healthcare-pharmaceuticals/patients-push-back-against-novo-nordisk-move-scrap-an-insulin-product-2024-07-30/"
X Link 2024-07-30T20:00Z [----] followers, [---] engagements

"Congratulations @FaulknerKristen Olympic 🥇 @FaulknerKristen has a cool story. Overcame challenges including being DQ'ed from prior race for wearing a CGM last year Now she is an USA Olympic Gold medalist. Champion. https://www.cyclingnews.com/news/kristen-faulkner-disqualified-from-strade-bianche-for-wearing-glucose-monitor/ This shot of USA's Kristen Faulkner winning gold in women's road cycling is amazing 🤣🙌 Four cyclists were fighting for gold then Faulkner blew past them with [--] km left https://t.co/Keqp23owBh"
X Link 2024-08-04T16:51Z [----] followers, [---] engagements

"It is a miss oppurtinity to not have SCIENTIFIC experts break down physiology psychology etc. during: 1) Olympics 2) Survival shows 3) Any athletic event Would add a whole new layer & Promote insights on the event most would find fascinating"
X Link 2024-08-11T21:17Z [----] followers, [----] engagements

"Interesting hypothesis. Although what happens when you actually test it @PhilipPrins11 @ProfTimNoakes https://pubmed.ncbi.nlm.nih.gov/36845048/ Carbohydrate 🍞restriction increases protein oxidation and impairs muscle hypertrophy 💪and anaerobic performance🏋♀: https://t.co/HK2bGNFXtY https://pubmed.ncbi.nlm.nih.gov/36845048/ Carbohydrate 🍞restriction increases protein oxidation and impairs muscle hypertrophy 💪and anaerobic performance🏋♀: https://t.co/HK2bGNFXtY"
X Link 2024-08-27T22:10Z [----] followers, [----] engagements

"This publication is one of dozens.but this is just the tip of the iceberg. There are now [--] publications in either low or very low carb diets in T1D. Publication coming soon. 🚨 NEW STUDY 🚨 This new study demonstrates that therapeutic carbohydrate reduction (TCR) can significantly improve time-in-range and the glucose management index (GMI) in children and young people with Type [--] diabetes which are critical markers of better glycemic control. https://t.co/3SAG49ddEl 🚨 NEW STUDY 🚨 This new study demonstrates that therapeutic carbohydrate reduction (TCR) can significantly improve"
X Link 2024-09-10T14:40Z [----] followers, [---] engagements

"🚨🍫Artificial Sweeteners & Metabolic Health: -Sucralose -Stevia -Monk Fruit -Allulose Are these harmful or helpful Full breakdown 👇 https://www.youtube.com/watchv=iTnYzNgL8Hs https://www.youtube.com/watchv=iTnYzNgL8Hs https://www.youtube.com/watchv=iTnYzNgL8Hs https://www.youtube.com/watchv=iTnYzNgL8Hs"
X Link 2024-10-06T00:48Z [----] followers, [---] engagements

"@BluesteinLinda @R_Mohr @hubermanlab @scicommedia I think people are unaware of how to make it sustainable. It is an education process. If that education is in place then I think it becomes much more sustainable"
X Link 2024-10-09T01:13Z [----] followers, [--] engagements

"Day 2: 🚗 Family Cross Country Tour CA - FL 🏔Yosemite National Park + Sierra National Park #Type1Diabetes #nationalpark #DadLife #yosemite #glucose"
X Link 2024-11-03T16:19Z [----] followers, [---] engagements

"Type [--] Diabetes 🚗 Family Cross Country Tour CA - FL Day 4: NV - AZ - UT 💦 Hover Dam 🏜 Zion National Park 🚜 UT Farm Stay #nationalpark #DadLife #Zion #glucose"
X Link 2024-11-05T17:39Z [----] followers, [---] engagements

"Type [--] Diabetes 🚗 Family Cross Country Tour CA - FL Day 5: AZ (Zion) - Flagstaff AZ 🏜 Zion National Park (Part 2) #Type1Diabetes #nationalpark #DadLife"
X Link 2024-11-06T17:33Z [----] followers, [---] engagements

"When studying this on an individual level it varies quite a lot. There have been reported cases in the literature of up to 14mM fasting without adverse symptoms (going decades back). There are also a well known discrepancies between cell concentrations and physiologic concentrations but this is often done as proof of concept to see dose-response as many cell lines are resistant to changes at physiological concentrations as they also become altered by multiple passes freeze/thaw cycles/etc. Doesn't mean it will not translate (also doesn't mean it will) hence why the multiorgan physiologic"
X Link 2024-11-11T12:57Z [----] followers, [---] engagements

"🚨"It's time to pull back the curtain on type [--] diabetes." -@maxdomi #NationalDiabetesDay Episode [--] of "In Range" is live. Check it out: -Spotify: -YouTube: -Apple Podcast (coming soon) https://youtu.be/tAwnnGWwy8E https://open.spotify.com/episode/3pc8HS67nlFAFae9J8nfOM https://youtu.be/tAwnnGWwy8E https://open.spotify.com/episode/3pc8HS67nlFAFae9J8nfOM"
X Link 2024-11-14T22:18Z [----] followers, [---] engagements

"🤯 🥞📈Ultra-Processed Food (UPF) & Energy Density PRELIMINARY data 🚨🚨CRAZY.CALORIC INTAKE & body FAT as you incorporate UPF with higher energy density and hyperpaletability. .UP TO [----] extra CALORIES/DAY @RobertKennedyJr @DrJBhattacharya see @KevinH_PhD thread below on their team's preliminary study outcomes 👇 This was a fascinating meeting on UPF policies and I was happy to present some preliminary results of our ongoing RCT on mechanisms by which diets high in UPFs cause excess energy intake. Heres a brief summary 🧵 This was a fascinating meeting on UPF policies and I was happy to"
X Link 2024-11-27T12:51Z [----] followers, [---] engagements

"".consensus statement conducted by the SMHP advocates for open access and clinical support for TCR nutrition interventions for individuals with T1DM across all age groups.""
X Link 2024-12-01T00:02Z [----] followers, [---] engagements

"🚨 Landmark consensus on ketogenic therapy for glioblastoma 🧠⚡ Glioblastoma one of the deadliest cancers sparked the metabolic therapy movement nearly a decade ago. Now thought leaders unite to define a clinical research framework for ketogenic strategies in GBM. Science evolves. 🚀👇 🔗 @drtomasduraj @tnseyfried @DrJosephMaroon @DominicDAgosti2 https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03775-4 https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03775-4"
X Link 2024-12-06T10:21Z [----] followers, [----] engagements

"👀 Pay attention to this 👇 👨🔬Type [--] diabetes is THE human insulin knockout. 🧪🔬You have total control over two of the MOST critical metabolic molecules: INSULIN & GLUCOSE. 🧠 What you can learn from T1D is incredibly insightful. 😔 Yet.virtually all patients with T1D are expected to get a long term complication from managing this disease. Is there a different way 🤔 A new publication sets up therapeutic carbohydrate reduction to become standard of care in Type [--] Diabetes. Only 21% of individuals living with type [--] diabetes (T1D) manage to achieve the target A1C level of under 7a target"
X Link 2025-01-01T21:18Z [----] followers, 12.4K engagements

"@euglycemic I hear you. Two of the critical management components in diabetes is 1) glycemic control 2) insulin sensitivity (lowering insulin requirements and engaging in exercise)"
X Link 2025-01-02T11:32Z [----] followers, [--] engagements

"This question assumes you can get glucose and glutamine to zero in physiology. You can't. Question is which cancers are effected by reduced availabilities of these molecules relative to normal. Also realize a solid cancer mass is never composed of one type of cell. This means the metabolic phenotype of a cancer cell from one spot in the tumor may be different than another despite the cancer have the same origin. This also applies for cancers in different parts of the body"
X Link 2025-01-06T20:23Z [----] followers, [----] engagements

"🍞 "Carbohydrates are the most overrated fuel in Type [--] Diabetes" -@maxdomi Is this true 📈 In the context of type [--] diabetes carbohydrates have the largest impact on glucose elevation and variability. 🔬The fastest acting insulin (ultra rapid) in type [--] diabetes is 3-4x slower than the insulin speed required to appropriately metabolize the glucose impact of complex carbohydrate digestion. So what does this mean 🏋♂🏃♂Carbohydrates have their place in performance. However the question is what is optimal and in what circumstances 🤨If arguably the most powerful hormone that facilitates the"
X Link 2025-01-07T20:36Z [----] followers, [----] engagements

"🧵Very-low carb (ketogenic; LCHF) vs high-carb diet (HCLF): -Ironman triathletes (n=10)🚴♂ -"Hitting the Wall"🥵 -Homeostasis monitoring ("Keto-Adaptation")📈 Our hypothesis was wrong.again 🔍CRITICAL QUESTIONS: 1) Does adopting an LCHF diet impair strenuous time-to-exhaustion performance 2) Does carb supplementation (3.4g/20min) during exercise 6-12x lower than current CHO fuelling recommendations improve time-to-exhaustion on LCHF If so how 3) Keto-adaptation homeostasis timeline 🔏KEY CONTROLS: 1) Randomized & Controlled 2) ❎Crossover Design 3) Calories 4) Physical Activity Load 5) Dietary"
X Link 2025-01-10T19:47Z [----] followers, 300K engagements

"Study Design: 🧍♂Ironman Competitors (VO2max) 🚴Performance: 4x Time-to-exhaustion (70% VO2max) 🔬Metabolism: 24h/7 Metabolite & Substrate Oxidation LCHF (42 Days): Glycogen Glucose Ketones FAT oxidation CHO oxidation Performance 2/n https://journals.physiology.org/doi/abs/10.1152/ajpcell.00583.2024 https://journals.physiology.org/doi/abs/10.1152/ajpcell.00583.2024 https://journals.physiology.org/doi/abs/10.1152/ajpcell.00583.2024 https://journals.physiology.org/doi/abs/10.1152/ajpcell.00583.2024"
X Link 2025-01-10T19:47Z [----] followers, 11.2K engagements

"@lavnderamethyst @_daniel_riley @PhilipPrins11 @DominicDAgosti2 @TheNoakesF @theplews1 @LoreofRunning1 @Jeukendrup @B_Holmer @sweatscience @tednaiman @AJPCellPhys Yes. Sort of. On a ketogenic diet FFA becomes the primary fuel substrate. Ketones are a byproduct of FFA/fat metabolism. Ketones are also an important fuel substrate but quantitatively FFA Ketones"
X Link 2025-01-11T09:25Z [----] followers, [---] engagements

"Just realized you can click posts and @grok button (top right) and it summarizes the posts (accurately). Interesting 🤔 🧵Very-low carb (ketogenic; LCHF) vs high-carb diet (HCLF): -Ironman triathletes (n=10)🚴♂ -"Hitting the Wall"🥵 -Homeostasis monitoring ("Keto-Adaptation")📈 Our hypothesis was wrong.again 🔍CRITICAL QUESTIONS: 1) Does adopting an LCHF diet impair strenuous time-to-exhaustion https://t.co/8HdoEmKu32 🧵Very-low carb (ketogenic; LCHF) vs high-carb diet (HCLF): -Ironman triathletes (n=10)🚴♂ -"Hitting the Wall"🥵 -Homeostasis monitoring ("Keto-Adaptation")📈 Our hypothesis was"
X Link 2025-01-13T18:41Z [----] followers, [----] engagements

"@charbrisc @exfatloss @KetoCarnivore @Leo_Abstract @raphaels7 @sudas1891 @CarnivoreAugust @DikemanDave Chris all my results and approaches have been detailed across two 10-year reports here: Can also see more details at http://Andrewkoutnik.com https://academic.oup.com/jcemcr/article/2/7/luae102/7710382login=false https://journals.physiology.org/doi/abs/10.1152/ajpcell.00694.2023journalCode=ajpcell http://Andrewkoutnik.com https://academic.oup.com/jcemcr/article/2/7/luae102/7710382login=false https://journals.physiology.org/doi/abs/10.1152/ajpcell.00694.2023journalCode=ajpcell"
X Link 2025-01-14T09:51Z [----] followers, [--] engagements

"@KetoCarnivore @charbrisc @DikemanDave @exfatloss @Leo_Abstract @raphaels7 @sudas1891 @CarnivoreAugust I have done close to 40% years back with a very bodybuilder focused mindset. It was work to get that amount in. However I am closer to 27% and see nothing added benefit to going higher in my case https://academic.oup.com/jcemcr/article/2/7/luae102/7710382login=false https://academic.oup.com/jcemcr/article/2/7/luae102/7710382login=false"
X Link 2025-01-14T09:53Z [----] followers, [---] engagements

"@charbrisc @ItIsMikeFitz @DikemanDave @exfatloss @KetoCarnivore @Leo_Abstract @raphaels7 @sudas1891 @CarnivoreAugust Bodybuilders consume crazy high levels of protein. Usually well north of 1g/1lb. Bodybuilders are also incredibly precise with food quantification. Most have hime scales for food. If I were to be the most precise community for protein tracking is probably the BB community"
X Link 2025-01-14T17:36Z [----] followers, [--] engagements

"@exfatloss @Leo_Abstract @ItIsMikeFitz @charbrisc @KetoCarnivore @DikemanDave @raphaels7 @sudas1891 @CarnivoreAugust Exogenous insulin shuttles relatively more nutrients to peripheral tissue. BOTH: muscle AND fat"
X Link 2025-01-14T17:43Z [----] followers, [---] engagements

"Note that insulin does a better job of storing fat than muscle growth. It blunts muscle catatonic processes and does a minor job of augmenting muscle growth (MPS). It doesn't build it directly. It does store fat directly. Insulin is a more powerful fat storage hormone than muscle"
X Link 2025-01-14T17:50Z [----] followers, [---] engagements

"@charbrisc @exfatloss @ItIsMikeFitz @DikemanDave @KetoCarnivore @Leo_Abstract @raphaels7 @sudas1891 @CarnivoreAugust Charles there may be some who do that but having been in the bodybuilding community for over a decade in my late teens and early 20s that is not at all what I saw (natural amateurs to pros). Carbs are huge in that community also"
X Link 2025-01-14T21:42Z [----] followers, [--] engagements

"@jeanpaulblartre @exfatloss @Leo_Abstract @ItIsMikeFitz @charbrisc @KetoCarnivore @DikemanDave @raphaels7 @sudas1891 @CarnivoreAugust Bodybuilders were doing this not realizing what it was doing. Some died doing it. But yes they still do this"
X Link 2025-01-14T21:58Z [----] followers, [--] engagements

"Potential delay in onset Possible. Cure No. DPP4i is the one that sticks out. Of all the therapies which have shown the ability to extend the honeymoon period (medication nutritional interventions etc.) they all that control glucose lower insulin requirements and/or simulate caloric restriction pathways"
X Link 2025-01-15T21:12Z [----] followers, [---] engagements

"@FructoseNo @DikemanDave @TypeOneGrit @DiabetesAus @JDRFaus @cadiulus @Type1Berger @type1sophie @Type1Roman @martykendall2 @foundmyfitness @DrJBhattacharya Carbohydrate restriction has shown this in multiple case reports. We have an NIH grant studying this right now. GLP1a with carbohydrate restriction has also shown this"
X Link 2025-01-15T21:13Z [----] followers, [---] engagements

"@Gonzalez_JT @LoreofRunning1 @ProfTimNoakes @timpodlogar @mike_williams73 @DrBSteamjets @jp_walhin @campbellmenz @AaronHengist @theplews1 All studies under [--] weeks have measured a deficit. If there is an exception I am unaware. Always a spectrum in science but I totally agree that removing assumptions with direct measures is higher scientific value"
X Link 2025-01-16T22:06Z [----] followers, [---] engagements

"I'm not pretending to have the answers. Super encouraged when that announcement came out. These are incredibly powerful tools for good and bad. If they were specifically set up to help people improve and become better people that could be one of the greatest humanitarian oppurtunities"
X Link 2025-01-18T16:10Z [----] followers, [--] engagements

"Never knew Bacteroides vulgatus increases GLP1a to supraphysioligic levels and keeps it elevated four days at a time 🤣 👨🏿🔬🧫Joke aside the actual discovery from the scientists in Nature Microbiology is an incredible finding and does link correcting endogenous GLP1 to gut health with POTENTIAL roles in diabetes glycemic control. There is growing evidence for correcting endogenous GLP1 for other therapies as well which have shown real-world data in humans. However. therapeutic application of individual gut species in HUMANS is lacking. Alot of associative data not alot of direct"
X Link 2025-01-21T13:12Z [----] followers, [----] engagements

"@hubermanlab @NIH @DrJBhattacharya @RobertKennedyJr A collab NIH submission going in this Feb so very curious to get insight"
X Link 2025-01-23T14:20Z [----] followers, [----] engagements

"@JWLevitt [----] Forest Gump 1/2 & FULL special edition release"
X Link 2025-01-23T16:56Z [----] followers, [---] engagements

"@ItIsMikeFitz @KenDBerryMD Whatttttt You take anabolic hormones 🤣 😂"
X Link 2025-01-28T01:47Z [----] followers, [--] engagements

"@zbitter @davidgoggins I believe according to @davidgoggins did all his loading going from minimal/no running to 100mile track run. I believe they call this exponential non-linear hyper-progressive potential death loading 😀"
X Link 2025-02-03T18:57Z [----] followers, [--] engagements

"🚨🚴♂World-class triathlete Lionel Sanders just dropped a bombshell: hes pre-diabetic. .true BRAVERY by Lionel but shocking Not to us. In [----] we uncovered "very fit" runnersVO2Max & Body Fatsilently battling the same. ☹Skeptics laughed. Yet.docs and athletes DMd us: 'Were seeing it too.' We ran an analysis on 24-hour glucose data in athletes Eye-opening at the incidence of level 100mg/dL. 📊🧑🍳We re-ran another analysis on what predicted elevated fasting glucose values in athletes. Shockingly BMI and fitness level (VO2Max) DID NOT predict basal glucose metabolism/health over time. What did"
X Link 2025-03-03T15:42Z [----] followers, 214.3K engagements

"@Rubyarguijo @Pinktelegirl @LoreofRunning1 @zbitter @B_Holmer @hubermanlab @CaseyMeansMD @calleymeans @bryan_johnson @BenBikmanPhD @DominicDAgosti2 @ChrisPalmerMD In Lionel's case he has confirmation from 24h average CGM reading including fatigue and impaired recovery symptoms. When he changed his diet his numbers and these symptoms improved"
X Link 2025-03-04T01:53Z [----] followers, [--] engagements

"@theproof @theproof You have discussed CVD alot 1) Why are real early signs of CVD progression and atherosclerosis not checked early in the disease process instead looking as risk biomarkers. These could be adapted to clinical settings 2) What do you consider these biomarkers"
X Link 2025-03-14T11:53Z [----] followers, [---] engagements

"@drjamesdinic . this is all interesting much respect.but if it were true where is the data on rapid muscle wasting on calorically controlled ketogenic diets where muscle was accurately assessed. Its not there. I know these calculations. I have seen some of the original and presented on them numerous times related to Cahill's work. I studied muscle catabolism in ketosis for my Read if you want to fall alseep. @DoctorTro @ProfTimNoakes @Metabolic_Mind https://digitalcommons.usf.edu/etd/8961/ https://digitalcommons.usf.edu/etd/8961/"
X Link 2025-03-19T17:50Z [----] followers, [----] engagements

"@GareyCozad @ProfTimNoakes Discussed here: https://substack.com/home/post/p-154543219 https://substack.com/home/post/p-154543219"
X Link 2025-03-21T19:34Z [----] followers, [--] engagements

"Ethan do you think what occurred to cause initial plaque is likely altering risk of future plaque In cancer cancer at a primary site will grow alter metastasis and initiate new cancer sites. Having cancer once dramatically increases the risk of future cancer with evidence showing that some cells may be dormant and develop to therapeutically resistant.so on and so forth. Depending on how you are viewing this cancer is an example of one begeting more at different sites In plaque not so much but risk may be altered Thoughts"
X Link 2025-04-09T17:05Z [----] followers, [---] engagements

"@Kidfears99 Laura what you do and dont do makes a MASSIVE difference. Many things in diabetes you cant do much about but on the whole patients have considerable control over how things go"
X Link 2025-04-13T17:54Z [----] followers, [--] engagements

"🥇Dr. Richard Bernstein was an advocate against many odd. A real pioneer in the field of Type [--] Diabetes. He helped a tremendous amount of people living with this disease. He lived to over [--] years of age. Incredible legacy. 🙏 Dr. Bernstein passed away last night. I will share more details as they become available. https://t.co/5FeJczOdiQ Dr. Bernstein passed away last night. I will share more details as they become available. https://t.co/5FeJczOdiQ"
X Link 2025-04-15T22:24Z [----] followers, [----] engagements

"@zbitter These extreme reactions are not going away. Very little has changed in the weight of the evidence in short periods. It fascinating seeing the trends come and go. As an examples recently it is high protein. That was evidenced based [--] decade ago but popular now"
X Link 2025-05-18T22:54Z [----] followers, [---] engagements

"@drterrysimpson @Delta Thank you Terry This is our first international flight since children"
X Link 2025-06-08T19:07Z [----] followers, [--] engagements

"80/20 Rule in Health Most health strategies are beneficial and dose-dependent up to diminishing returns. Examples: Exercise & Glucose 1) Exercise: [----] steps or [---] MET-min/week yield most health benefits. More exercise adds benefits.but marginal.is the extra time worth it 2) Glucose Control: In diabetes management HbA1c of 5.45.5% reduces most complications and hazard ratios to a clear plateau. Is spending an additional [----] hours/week to achieve 5.4% worthwhile Maybe.but for most maximizing return on investment to maximize 80% yield from your time investment and then spending the remaining"
X Link 2025-06-19T10:40Z [----] followers, 16.3K engagements

"@hubermanlab @B_Holmer @stevemagness No parachute.☠"
X Link 2025-06-19T21:28Z [----] followers, [---] engagements

"#ADA2025 Excitement for Pharma vs Lifestyle We are all excited for pharma and tech innovations.but this photo looks like it was taken out of a meme generator.😄 🤣 Trying to get into the session on small molecule GLP1RA was like trying to get into a rock concert. Huge interest. Good thing ACHIEVE-1 is published https://t.co/SAGxl6OHbF #ADASciSessions https://t.co/mnGSYgpPQ9 Trying to get into the session on small molecule GLP1RA was like trying to get into a rock concert. Huge interest. Good thing ACHIEVE-1 is published https://t.co/SAGxl6OHbF #ADASciSessions https://t.co/mnGSYgpPQ9"
X Link 2025-06-22T11:24Z [----] followers, [----] engagements

"To be clear.NO the data doesnt say if you put a CGM on it magically fixes your metabolism. They require educated guidance on what to do with the information and their limitations. But in the right environment.I woukd argue they may be the best real time tool we have for some specific lifestyle monitoring"
X Link 2025-06-28T12:15Z [----] followers, [---] engagements

"Data says it doesnt necessary lead to weight loss if you just strap it on. Weight loss requires guidance on how to alter nutritional intake while CGM can provide some signal on how dietary change may effect metabolism. Can be valuable in the right context but if you just put one in a line with little guidance it does very little"
X Link 2025-06-29T16:28Z [----] followers, [---] engagements

"Blood Glucose Range: -70-120 -70-140 -70-180 Where do these come from What is the risk Below [--] mg/dL: Triggers neuroendocrine responses to hypoglycemia. Key Ranges: 70-120 mg/dL: Typical daily range for most HEALTHY patients though fasting levels may vary by [--] mg/dL. 70-140 mg/dL: Healthy individuals with normal insulin sensitivity usually stay below [---] despite mixed diet. 70-180 mg/dL: Above [---] diabetes complication risks rise significantly. .HOWEVER we start seeing almost a DOUBLING of risk when HbA1c rises from normal to pre-diabetes range and then rises RAPIDLY as it goes higher."
X Link 2025-06-29T22:47Z [----] followers, [----] engagements

"🌏 Real-World v Pharma Trial Results: GLP1Ra 💉 [-----] patients 2-Years Treatment GLP1Ra: real-world data 5% weight loss.compared to 15-25% reported in Lilly & NovoNordisk results).oops. 😓 What happens in the real world isn't always what happens in long term RCTs 🤷♀"
X Link 2025-06-30T13:35Z [----] followers, [----] engagements

"@GaylaHolmer @B_Holmer @bryan_johnson MOMMA GAYLA plays no games"
X Link 2025-07-02T21:35Z [----] followers, [--] engagements

"This whole exchange is incredible"
X Link 2025-07-02T21:37Z [----] followers, [----] engagements

"🧠New Ketogenic Diet Study in Glioblastoma (GBM) 📊Phase I Pilot: -Overall survival: 30months -Historical overall survival: [--] to 16months Near doubling.Phase II is recruiting"
X Link 2025-07-03T16:32Z [----] followers, [----] engagements

"Retatrutide Seems similar to high dose Tirzepatide. .but the emergent triple GLP1Ra agonists and other derivatives are likely going to be way more powerful. I think it will reach the point where hunger will be virtually eliminated through pharmaceuticals. Whether that is good or bad is a separate question"
X Link 2025-07-07T18:21Z [----] followers, [---] engagements

"These drugs lower glucagon (in part) by enhancing endogenous insulin release inducing a paracrine effect on glucagon release at alpha cells. In T1D this mechanism cannot be leveraged. These drugs' pleiotropic impact in obesity and T2D will not be as potent in T1D for this reason"
X Link 2025-07-07T18:31Z [----] followers, [---] engagements

"@SamueleMarcora .or using their training and nutritional advice. If it isnt used in elite many high level academic discount it. Yet elite is 0.01%"
X Link 2025-07-09T12:09Z [----] followers, [--] engagements

"@bryan_johnson If you need to hear this advice you have much bigger problems than cognitive function at work"
X Link 2025-07-09T18:05Z [----] followers, [---] engagements

"🫀Breakthrough Alert: First FDA-Approved Cuffless Continuous Blood Pressure Monitor Hilo (formerly Aktiia) just made history with the first-ever FDA approval for a cuffless continuous blood pressure (BP) monitoring device. A decade ago I used a $20000 version of this tech in a research lab. Now its affordable and available to everyone Why this matters: Monitoring BP isnt just a numberits a game-changer for health. High BP drives early vascular and heart remodeling fueling Cardiovascular Disease (CVD) the #1 killer. Its also a top modifiable risk factor for CVD and the #2 modifiable risk"
X Link 2025-07-10T11:45Z [----] followers, [----] engagements

"Bold New Study Title: "Ketogenic Diets Are Associated with an Elevated Risk for All Cancers" Yet the lowest average carb intake was 180g/day. 😣"
X Link 2025-07-15T07:56Z [----] followers, 56.8K engagements

"@BrundoCoban Agree data supporting diets role exists all over. DLW method used by @HermanPontzer is quite important here to the methods"
X Link 2025-07-16T13:36Z [----] followers, [--] engagements

"🐁 New Mouse (WITHOUT NNT) Study Suggest Ketogenic Diet Induced Oxidative Stress in Male but NOT Female 💥 🤔Interesting this doesn't seem to be the case in humans 🔬Insight: [--] years ago I found that mouse models lacking NNT (key enzyme balancing mitochondrial ROS and inflammation) exhibited adverse responses to ketosis (diet and supplemental). 🧍♂Humans have NNT. 🐁Mouse models often lack NNT (due to chronic inbreeding) Look at the study by study differences in mouse models with and without NNT in Ketogenic diet studies.you will see something interesting"
X Link 2025-07-21T09:45Z [----] followers, [---] engagements

"Calley to be clear. @AmerAcadPeds also put out a statement discouraging low-carbohydrate diets in children with juvenile diabetes.but cited ZERO primary literature in juvenile diabetes supporting this recommendation. Discussed this trend before https://x.com/AKoutnik/status/1929547474852606310 https://pubmed.ncbi.nlm.nih.gov/37718964/ https://pubmed.ncbi.nlm.nih.gov/37718964/ https://x.com/AKoutnik/status/1929547474852606310 https://pubmed.ncbi.nlm.nih.gov/37718964/ https://pubmed.ncbi.nlm.nih.gov/37718964/"
X Link 2025-07-22T17:22Z [----] followers, [----] engagements

"@foundmyfitness Hopeful. .monitoring a protein presents unique challenges unlike a metabolite. Will be curious to what tech allows this"
X Link 2025-07-31T20:49Z [----] followers, [---] engagements

"@StevenQuartz Steven.5 hour bike ride That was your first mistake.RIP ☠"
X Link 2025-08-03T14:21Z [----] followers, [---] engagements

"Blood Glucose: In those who still have endogenous insulin secretion blood glucose is often the LAST SIGNAL for a host of (negative) changes in metabolism. Once glucose rises it often has often been preceded by years of elevated insulin value (double quadrupled or more.) Adiposity: We know that being obese and having excess adiposity and being "healthy".is unlikely. I would argue it is NEVER optimal for health (within this context) I would not buy anyone arguing excess adiposity is equivalent for aging based on a number of well done studies looking at "Metabolically Healthy Obese" versus"
X Link 2025-08-06T11:16Z [----] followers, [----] engagements

""Ozempic didnt work for me. I was furious and ashamed." -Patient with Type [--] Diabetes ☹I was recently interviewed for an article in the Guardian from a patient with Type [--] Diabetes who tried GLPR1a and was unable to find weight loss. They described frustration and shame. Really important discussion on what happens when it doesn't work. 🔗Link below👇"
X Link 2025-08-15T11:41Z [----] followers, [----] engagements

"@sugarliberated @DamionKnudsen @Metabolic_Mind @FSUISSM @janellison @BenBikmanPhD @DoctorTro @DominicDAgosti2 @DrNadolsky @bschermd @nicknorwitz @garytaubes You can https://academic.oup.com/jcemcr/article/2/7/luae102/7710382 https://journals.physiology.org/doi/full/10.1152/ajpcell.00694.2023 https://academic.oup.com/jcemcr/article/2/7/luae102/7710382 https://journals.physiology.org/doi/full/10.1152/ajpcell.00694.2023"
X Link 2025-08-16T09:48Z [----] followers, [--] engagements

"🧵NEW STUDY: Low-carb vs high-carb pre-exercise meals -Middle-distance runners (n=30)🏃♂ -"Carbohydrate oxidation performance myth"🤯 -2X pre-exercise meal performance testing📈 Our assumptions challenged.again. 🔍CRITICAL QUESTIONS: 1) Does LOW-CARB pre-exercise meal shift to fat oxidation and impair time trial performance 2) How do metabolite profiles like ketones and glucose differ and affect outcomes 3) Individual variability in responses 🔐 KEY CONTROLS: 1) ❎Randomized crossover design. 2)Isocaloric meals. 3)Controlled diet activity bodyweight. 4)✅Fed state to avoid glycogen/hypoglycemia"
X Link 2025-08-27T13:16Z [----] followers, 96.7K engagements

"Great to see other's interpretation. @JeroenSwart makes good points but we cannot assume longer or altered N will guarantee a different outcomes. That is NEVER a guarantee (speaking from direct experience). This is great research. High quality design and execution. Butas with most LCHF studies the proponents are not neutral and border on religious levels of fervour. Lets look at the data more closely. This is great research. High quality design and execution. Butas with most LCHF studies the proponents are not neutral and border on religious levels of fervour. Lets look at the data more"
X Link 2025-08-28T13:24Z [----] followers, [---] engagements

"🍫☠Ultraprocessed Foods are now OFFICIALLY associated with mortality. 🍭Multiple forms of sugar sweetener agents flavor agents and coloring agents all associated with increased mortality. 👉Modified oil and fiber were not"
X Link 2025-09-02T21:49Z [----] followers, [----] engagements

"🚨BIG NEWS: $50M Investment to End America's Health Crisis🚨 🔬I'm Andrew Koutnik PhD in Nutrition Metabolism & Diabetesand a patient living with an irreversible chronic metabolic disease. Thrilled to advise the NEW Coalition for Metabolic Health LAUNCHED to REVERSE our chronic disease epidemic Our [--] BOLD objectives: 1Push policy shifts for science-based nutrition guidelines research screenings & insurance. 2Fund unbiased research to empower docs & public with real metabolic insights. 3Educate providers policymakers & YOU on metabolism's power to prevent/reverse disease. 4Incorporate"
X Link 2025-09-04T15:11Z [----] followers, 27.4K engagements

"Grateful to @StevenBartlett for the chance to share my storygrowing up with obesity & diabetes facing childhood chronic disease firsthand and now dedicating my life to uncovering solutions. 🔬 This is about hope resilience & empowerment for those with chronic disease. ❤ What if the food you eat every day is slowly damaging your health Were surrounded by so many diets and endless advice that is conflicting which leaves most of us confused. So I wanted to sit down with someone who has studied and lived it for their whole life. Dr Andrew https://t.co/sPH2GnyWtI What if the food you eat every day"
X Link 2025-09-08T09:35Z [----] followers, 27.4K engagements

"@janellison @P_McCulloughMD @nicknorwitz Can't leave a comment on his substack without paid subscription. Smart businessman 😄 @davidludwigmd set up a debate on this exact topics in AJCN with Ron Krauss & Penny Kris-Ethernlton. It is clearly not cut and dry: https://pubmed.ncbi.nlm.nih.gov/32491172/ https://www.sciencedirect.com/science/article/pii/S000291652200764X https://pubmed.ncbi.nlm.nih.gov/32491172/ https://www.sciencedirect.com/science/article/pii/S000291652200764X"
X Link 2025-09-18T16:37Z [----] followers, [---] engagements

"🧈🫀Saturated fat LDL-C and CVD: @davidludwigmd set up a debate on this exact topic in AJCN with Ron Krauss & Penny Kris-Etherton. It is clearly not cut and dry: More importantly. @janellison has contributed more (maybe than anyone) to advancing our understanding of nutrition's role in health recently. voluntarily with her time resources and passion. She's not just engaging in scientific discourse at a table she is about action. @P_McCulloughMD's attempt to secretly insult others is pathetic. Do better Peter. https://pubmed.ncbi.nlm.nih.gov/32491172/"
X Link 2025-09-18T16:50Z [----] followers, [----] engagements

"New Report: LDLc of [---] mg/dL for [--] Years on Ketogenic Diet Atherosclerosis No sign This case report is aligned with our 10-year longitudinal data in a high risk CVD setting: This does not mean high LDL-C is "good".but it does present counter intuitive data on diet and CVD. https://journals.physiology.org/doi/full/10.1152/ajpcell.00694.2023journalCode=ajpcell https://journals.physiology.org/doi/full/10.1152/ajpcell.00694.2023journalCode=ajpcell https://journals.physiology.org/doi/full/10.1152/ajpcell.00694.2023journalCode=ajpcell"
X Link 2025-09-27T11:50Z [----] followers, 66K engagements

"Yes but many patients with T2D in these GLP1-Ra trials are probably not all that far along. Pharma companies would also not want these patients in their trials since it would almost certainly make their drugs look like effective. Another contributor which gets little attention is disrupted glucose levels was demonstrated about a decade ago to disrupt GLP1 Agonist efficacy. I would be interested to see if therapies which 1) low insulin 2) normalize glucose .are sufficient to restore effectiveness of these drugs in patients with diabetes"
X Link 2025-09-28T21:58Z [----] followers, [---] engagements

"😡Misclassifying "Low-Carbohydrate" Diets in Diabetes👇 We have repeatedly put out clear definitions (JCI 2021) for "Low Carbohydrate Diets" (10-25% of total calories from carbohydrates; 50-130 grams/day). Sadly.even top research groups still don't understand this (see @nicknorwitz post below). A diet composed of 25-45% of calories from carbohydrates is MORE similar to a WESTERN DIET or Standard American Diet. and yes.you would expect that to worsen outcomes in Type [--] Diabetes. A true "Low Carbohydrate Diets" have shown in JAMA [----] to rapidly reduced glucose levels in patients with"
X Link 2025-10-01T21:10Z [----] followers, 12.1K engagements

"👇 How do we change a deteriorating health trajectory in the United States if we continue to do the same thing that got us there Why do we need a Coalition for Metabolic Health Because what were doing is failing miserably. We need a renewed commitment to metabolic health and an abandonment of the status quo. Read more on my new blog series on our CMH website. (Link in comment) Why do we need a Coalition for Metabolic Health Because what were doing is failing miserably. We need a renewed commitment to metabolic health and an abandonment of the status quo. Read more on my new blog series on our"
X Link 2025-10-03T00:50Z [----] followers, [----] engagements

"I respect this approach and agree it comes down to the individual and what works for them. Having researched this area for well over a decade I argue there is an unjustified level of negativity around the ketogenic diet and/or low carbohydrate diets. Negativity and stigma which is pervasive particular in institutions and guidelines. I know because I've been in those conversations. It has been around for [---] years preventing managing and reversing obesity and diabetes. [---] years for epislepsy. Etc. It is acknowledged as the most evidenced based diet by the ADA diet for T2D. Yet.there is alot"
X Link 2025-10-12T12:17Z [----] followers, [----] engagements

"What is the most unhealthy professional sport My answer = Bodybuilding. 🫀📈Any other professional sport where there is a 5-fold higher risk for sudden death amateurs - elites @MrOlympiaLLC"
X Link 2025-10-13T11:48Z [----] followers, 11.7K engagements

"@longevity_agent @B_Holmer @doctorinigo @LoreofRunning1 @PhilipPrins11 @BenBikmanPhD I dont think they are asking important as many have argued. I suspect minimal levels are sufficient to extract most/all their benefits"
X Link 2025-10-14T14:00Z [----] followers, [---] engagements

"@JoseAntonioPhD @MrOlympiaLLC @caloriesproper2 @DrKarlNadolsky @DrNadolsky @BioLayne @ThomasDeLauer @drmikeisraetel @JeffNippard @EricTrexler @BradSchoenfeld @TheAlanAragon Yea yea Jose 😄 🤣"
X Link 2025-10-14T23:35Z [----] followers, [---] engagements

"@caloriesproper2 @AllisonEthier @MrOlympiaLLC @DrKarlNadolsky @DrNadolsky @BioLayne @ThomasDeLauer @drmikeisraetel @JeffNippard @EricTrexler @BradSchoenfeld @TheAlanAragon Very few sports require the frequency and volumes of very potent drugs like bodybuilding though. Some may content Tour De France os another example but they are normal BW and do aerobic exercise. Also they regulate that sport so it cant be 24/7"
X Link 2025-10-14T23:37Z [----] followers, [--] engagements

"Prepping for the holidays 🎄🔥 5x 502lb Hatfield Squats"
X Link 2024-12-14T11:54Z [----] followers, [---] engagements

"@MiriamETucker Great points. 💪 Insulin is essential & lifesaving. Important to also note that emergent evidence suggests: 1) Obesity increases the risk of T1D diagnosis particularly kids. ⚖📏 2) Reducing bodyweight reduces incidence of T1D diagnosis. 📉👍 3) Very small but interesting body of evidence that altering nutritional approaches may alter beta cell function (and in T1D extend honeymoon). 🍽 4) Different eating patterns induce diverse immunological function 5) Genetics at MOST explain 50% of newly diagosed T1D 🧬 This directly suggest environmental interactions with genetics may be a"
X Link 2025-02-15T08:48Z [----] followers, [--] engagements

"💊New Novo Nordisk CEO cancels "cure" for Type [--] Diabetes. After a failed [--] year journey to cure diabetes with cell therapy.Novo Nordisk CEO @maziardoustdar is reallocating resources to what they consider "high-priority areas" 💰 "Obesity and diabetes treatments." 📈Meaning the chronic "management" of metabolic disease with drugs.because it increases profit. 🙃Novo Nordisk will also cutting 11% of costs and [----] jobs to further increase revenue. Novo Nordisk made $260 Billion in [----]. PHARMA has promised and failed people with Type [--] Diabetes. Stop putting false hope in companies like this."
X Link 2025-10-11T12:04Z [----] followers, [----] engagements

"👩🍼🍼New study: Ketosis during weaning drives adipogenesis and offer a therapeutic approach to combat obesity and metabolic diseases in adulthood. https://www.nature.com/articles/s42255-025-01378-8 https://www.nature.com/articles/s42255-025-01378-8 https://www.nature.com/articles/s42255-025-01378-8 https://www.nature.com/articles/s42255-025-01378-8"
X Link 2025-10-17T14:14Z [----] followers, [----] engagements

"@Estebanarayag @ProfTimNoakes @drphilpdx @B_Holmer Lets be clear.those carbs at the end of a race are unlikely to have "topped off" glycogen levels in Tour De France. It is more likely the overnight IV glucose and peripheral exogenous insulin doing that"
X Link 2025-10-29T20:52Z [----] followers, [--] engagements

"@MichaelMindrum I think patients showing up with HbA1c 6.4% should AUTOMATICALLY be given a C-peptide and GAD assessment to rule out T1D. I think this should be the standard of care. If that is "too much" then the algorithm could indicate 30kg/m2 to set off those test with 6.4% HbA1c"
X Link 2025-11-02T12:56Z [----] followers, [---] engagements

"New: Ketogenic Diet Associated with Reduced Depression Scores in @JAMAPsych New meta analysis show ketogenic diet improves psychiatric scores compared to high carb diet. They also showed that ketogenic diet showed greater improvement than just going "low carb.""
X Link 2025-11-06T11:05Z [----] followers, 29.9K engagements

"New Meta Analysis of [---] Studies & [----] people shows that reducing carbohydrates: [--] improves glycemic control [--] reduces insulin [--] improves measures of insulin sensitivity Effects were most potent in: ♀ women 📏 obese 🩸 diabetes"
X Link 2025-11-07T12:00Z [----] followers, [----] engagements

"@mcuban as a patient (and researcher) with type [--] diabetes I have done this same exact calculation. It is 3x cheaper to do direct pay for all care compared to the total cost of insurance (insurance premiums co-pays etc.). The only problem is going bankrupt if you run into a life threatening diagnosis requiring hospital care and chronic management with expensive treatments (cancer is an example)"
X Link 2025-11-16T12:43Z [----] followers, [----] engagements

"If it does should it go to those who discovered GLP1 the molecule or to those who discovered how to create a molecule that actually elevates GLP1a to supraphysioligic levels which is what is what resulted in meaningful health differences. Physiologic levels do not product these same outcomes"
X Link 2025-11-16T13:02Z [----] followers, [---] engagements

"T1D vegan study with no glucose control outcome Yes.you expect low carb and vegetarian/vegan to reduce insulin requirements from standard diet approaches (for opposite reasons). HOWEVER the MAJOR limitation of a vegetarian/vegan approach are that carbs glucose kinetics DO NOT match injectable insulin kinetics. Carbs are 3-4x faster than the most rapid injectable insulin.and it just so happens that this study doesnt report glycemic control Glycemic control is the #1 risk factor. https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-025-01175-2"
X Link 2025-11-24T16:51Z [----] followers, [----] engagements

"Leaders in the diabetes space argue CGM should be used in Type [--] Diabetes. I agree"
X Link 2025-11-26T18:27Z [----] followers, [----] engagements

"2/n previously we showed no signs of cardiovascular disease in patient with Type [--] Diabetes on a ketogenic diet for [--] years.instead CV physiology was superior to non-diseased controls (see prior thread) .but main criticism no CAC score.so 👇 https://x.com/AKoutnik/status/1805290458500739307s=19 https://x.com/AKoutnik/status/1805290458500739307s=19 🔬🤯🫀 10-Years longitudinal data on KETOGENIC DIET and Safety Efficacy & Advanced Cardiovascular Physiology in a patient with HIGH RISK cardiovascular disease (Type [--] Diabetes) #ADA2024 NEW DATA OUT TODAY: https://t.co/kgSbLGiizN We"
X Link 2025-11-28T17:07Z [----] followers, [----] engagements

"3/n .so we assessed CAC the gold standard for CVD risk assessment in a patient with 10x higher CVD risk (i.e. Type [--] Diabetes) after adhering to ketogenic diet for [--] years and. .the calcium score was [--]. https://pubmed.ncbi.nlm.nih.gov/41289606/ https://pubmed.ncbi.nlm.nih.gov/41289606/ https://pubmed.ncbi.nlm.nih.gov/41289606/ https://pubmed.ncbi.nlm.nih.gov/41289606/"
X Link 2025-11-28T17:07Z [----] followers, [----] engagements

"@CRYPT0N1TE @Joseph_Watso @nicknorwitz @BenBikmanPhD @bigfatsurprise @garytaubes @bschermd @metcoalition @Metabolic_Mind @DoctorTro @janellison @lowcarbGP In the context of T1D where CVD risk is 10x higher and all patients are at immediate risk for insulin resistance due to exogenous insulin the risk is inherently higher so this is particularly important in this disease setting"
X Link 2025-11-29T20:46Z [----] followers, [---] engagements

"Maltitol spikes glucose. It is a sugar equivalent. Don't be fooled Oreo announces zero-sugar cookies. Maltitol polydextrose sucralose and ace-k have replaced the sugar. https://t.co/iKx9AQzsSF Oreo announces zero-sugar cookies. Maltitol polydextrose sucralose and ace-k have replaced the sugar. https://t.co/iKx9AQzsSF"
X Link 2025-12-12T18:34Z [----] followers, [----] engagements

"Ive noticed a pattern. Many people who call ketogenic carnivore low-carb etc. diets restrictive have never lived with obesity or managed a chronic metabolic disease themselves. For many patients these approaches arent restriction at alltheyre the first sense of freedom from food noise symptoms and suffering. Perspective matters. Listen to those whove lived it. Look for people whove walked the path youre trying to walk"
X Link 2025-12-27T19:10Z [----] followers, 54.7K engagements

"Jiu Jitsu has been unlike any sports I have trained or competed in. It is a beautiful yet incredibly challenging (especially to the ego). No excuses. No shortcuts"
X Link 2025-12-29T16:26Z [----] followers, [---] engagements

"What is the single greatest step you took for your health"
X Link 2025-12-29T20:20Z [----] followers, 62.6K engagements

"@jturley99 @nicknorwitz @janellison @garytaubes @DominicDAgosti2 @AdrianSotoMota @bigfatsurprise @bschermd @BaszuckiMatt @IainCampbellPhD Keep pushing you will eventually get a break through. It doesn't get easier but you get better"
X Link 2026-01-05T19:29Z [----] followers, [--] engagements

"🚨New Food Pyramid🍽 Major Overhaul: 1Protein prioritized. 2No sugar components. 3High glycemic foods are lower. https://twitter.com/i/web/status/2008974820839707012 https://twitter.com/i/web/status/2008974820839707012"
X Link 2026-01-07T18:51Z [----] followers, [----] engagements

"Biggest reset in U.S. nutrition policy in decades. 👇 90% of adults are metabolically unhealthybigger waistlines higher blood sugar higher triglycerides. We need guidance built for reality. And kids get 2/3 of calories from ultra-processed foods. These guidelines finally confront it. Bravo. Today @HHSGov and @USDA released the 2025-2030 Dietary Guidelines for Americans returning to a diet based on whole foods from plant and animal sources. The new pyramid opens the door to a revolution in American nutrition. Read our reaction: https://t.co/udDVmNYkbm Today @HHSGov and @USDA released the"
X Link 2026-01-08T09:47Z [----] followers, [----] engagements

"@SBakerMD ☝ there are some phenomenal athletes already doing this.might know one"
X Link 2026-01-21T12:54Z [----] followers, [---] engagements

"Altitude does seem to impact exogenous glucose oxidation We have done some studies with ketones as an alterantive approach and showed cognitive enhancement other have shown enhanced oxygen uptake in the muscle. However not sure if it translates to a direct performance effect but it certainly changes the biology of the athlete. https://pmc.ncbi.nlm.nih.gov/articles/PMC6046468/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6046468/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6046468/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6046468/"
X Link 2026-01-22T11:50Z [----] followers, [---] engagements

"@stevemagness poses a critical question many have asked. Please see the full response below if you have the same question. @AKoutnik @DominicDAgosti2 @sweatscience @Brady_H @JoseAntonioPhD @nicknorwitz @DoctorTro @NTFabiano @MitoPsychoBio @ChrisPalmerMD @nick_krontiris A simple and genuine question: How come this goes against everything that actual elite performers in the actual arena do and find helpful. If keto or any of these ideas have a significant advantage then after experimentation elites would surelytake them up. Or thered be a @AKoutnik @DominicDAgosti2 @sweatscience @Brady_H"
X Link 2026-01-22T23:57Z [----] followers, [----] engagements

"Steve Im totally aligned that what happens in the real world can often inform reality years (sometimes decades) before the science catches up. At the same time history also shows the opposite: many widely adopted practices were fundamentally flawed and science ultimately helped reverse them. And Ill reiterate something Ive said elsewhere because I think it matters. You came into the world of mindset/performance with ideas that challenged established coaching dogma took real backlash and kept going. You acknowledge this came from your own lived experience that went against an entire"
X Link 2026-01-23T11:39Z [----] followers, [---] engagements

"@wooddell_jim @stevemagness @DominicDAgosti2 @sweatscience @Brady_H @JoseAntonioPhD @nicknorwitz @DoctorTro @NTFabiano @MitoPsychoBio @ChrisPalmerMD @nick_krontiris Very common. Also common keto Athletes who then adapt dont realize carbs can still be used for long exercise Bout to enhance performance"
X Link 2026-01-24T11:01Z [----] followers, [---] engagements

"Another question Steve is do we think that the best in the world are the best in the world because of their diet Do we think that the reason they perform their best is because of the diet they choose That they consumed 120g/h instead of 30g/h You have repeatedly noted that people focus too much on things that have marginal impact. Instead they should be focusing on what actually matters Showing up. Training. Being consistent. Am I articulating your point correctly"
X Link 2026-01-24T14:22Z [----] followers, [----] engagements

"@AlanaNewmanCA We show that carbs do have a role. Its about precision and dose"
X Link 2026-01-24T18:22Z [----] followers, [---] engagements

"Steven great points. Question: we would expect this to show up in controlled laboratory setting where other confounders (not nutrient based) can be controlled then ofcourse correct If not where do you see the blindspot in the methodology of current experiment where repeated dont show this effect This may help us get to this answer"
X Link 2026-01-25T19:14Z [----] followers, [---] engagements

"@thegarybrecka should read our review. https://academic.oup.com/edrv/advance-article/doi/10.1210/endrev/bnaf038/8432248 Gary Brecka on why fasted high-intensity workouts (black coffee + Orange Theory hammer) often fail women: After [--] min glycogen's gonebody burns lean muscle for quick energy (3 min process) instead of fat (5+ hours). You rebuild overnight. repeat cycle = no net fat loss. His https://t.co/BmhNZwle2K https://academic.oup.com/edrv/advance-article/doi/10.1210/endrev/bnaf038/8432248 Gary Brecka on why fasted high-intensity workouts (black coffee + Orange Theory hammer) often fail"
X Link 2026-01-26T10:55Z [----] followers, [----] engagements

"@Brioneja if increasing carbohydrate intake during exercise in a dose-dependent manner drives the improvements. Would you expect that when a scientific experiment controlled the other confounders on performance and then actually tested the CHO dose-response effect they would see clear performance changes If so why is that evidence absent @stevemagness In the past few years professional bike riders have increased their carbohydrate intake from 60-90 g/hr to 120-140 g/hr with documented improvements in performance https://t.co/y6TGh2HKCR @stevemagness In the past few years professional bike"
X Link 2026-01-26T11:34Z [----] followers, [---] engagements

"🚨OUR NEW PUBLICATION: 🫀Ketogenic Diet [--] Years in a Patient with 10x Elevated Cardiovascular Disease = [--] Calcium Score. @Joseph_Watso 📖 Why is this so important 1/n 👇 https://pubmed.ncbi.nlm.nih.gov/41289606/ https://pubmed.ncbi.nlm.nih.gov/41289606/"
X Link 2025-11-28T17:07Z [----] followers, 113.7K engagements

"The only one who has been public (I will not disclose any other private names) is Lionel Sanders. We also showed 30% here: Lionel still does carbs (he is also spinsored bt a few sport companies) but cut back and shifted the type. To his anecdotal report he corrected his BG quickly. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1084021/full https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1084021/full"
X Link 2026-01-24T11:04Z [----] followers, [--] engagements

"Totally agree that a laboratory experiment such as our was not a 1-for-1 to real world. It cannot be (although that wasnt the point). We want to control the key confounding variables to test physiology of CHO variability in exercise. Also acknowledge your point on glycolysis key role during higher intensities.but please see below. 1) What do you make of our first study showing sustained performance at 6x800m sprints and 1mile time trial at 85%VO2max 2) What do you make of the physiologic phenomena that as you increase CHO intake to 120g/hour compared to 25g/hour you burn much high levels of"
X Link 2026-01-26T12:14Z [----] followers, [----] engagements

"🚨Our Landmark Sport Nutrition Analysis in Endocrine Reviews spanning 100+ years & [---] studies🔬 challenges the foundations of the sports nutrition industry & guidelines exposing potential harm to athletes' health. This is the most comprehensive pub on nutrition's impact on performance (5+ years in the making). What we found is critical to athletes coaches dieticians and the scientists who write guidelines with FREE study link below: 1) 🍞"Carb-loading" is misguided Current sport nutrition guidelines (i.e. @ACSMNews @IntSocietySN @Gatorade Sport Science Institute) recommend [---] g/kg CHO/day"
X Link 2026-01-21T11:19Z [----] followers, 185.3K engagements

""ChatGPT make a caricature of me with everything you know of my life""
X Link 2026-02-06T20:12Z [----] followers, [---] engagements

"RT @NTFabiano: [--] weeks without smartphone internet significantly improved sustained attention. The effects were similar to being a decade"
X Link 2026-02-08T21:13Z [----] followers, [----] engagements

"RT @NutritionMadeS3: This is an exaggeration and misses the point. Selling a product creates a bias but doesnt eliminate general credibili"
X Link 2026-02-09T16:28Z [----] followers, [--] engagements

"Beautifully well said. I keep seeing in the lab people who train consistently look fit race and do the right things. And yet metabolically many of them are far more fragile than they realize. Here are [--] ideas I want you to sit with: [--]. Performance and health are not the same thing = You can https://t.co/gAK8WBk5uk I keep seeing in the lab people who train consistently look fit race and do the right things. And yet metabolically many of them are far more fragile than they realize. Here are [--] ideas I want you to sit with: [--]. Performance and health are not the same thing = You can"
X Link 2026-02-07T18:09Z [----] followers, [----] engagements

"Football player sues for arguing he was benched due to a T1D diagnosis. Sad if true. Note many athletes reach the peak of their sport with T1D. I can lift plenty. https://www.sltrib.com/sports/utah-utes/2026/02/07/former-utah-utes-with-diabetes/ https://www.sltrib.com/sports/utah-utes/2026/02/07/former-utah-utes-with-diabetes/"
X Link 2026-02-09T13:43Z [----] followers, [---] engagements

"Scientist sell themselves in every single grant they right to the universities they work for etc etc.they are constantly selling. Just like @EricTopol is selling his book and his subscription platform I am confused Seems like the wrong target Topol: The same thing occurs with all these wellness influencersthe latest being Peter Attia. There are hundreds and hundreds of these so-called longevity hackers. One cardinal rule I have is this: if somebody is selling something they have no credibility. Zero. https://t.co/zIBEtxvPWT Topol: The same thing occurs with all these wellness influencersthe"
X Link 2026-02-09T16:28Z [----] followers, [----] engagements

"Caffeinated coffee associated with protection against dementia. Decaffeinated does not. ☕☕☕☕☕ Moderate consumption of caffeinated coffee or tea was linked to reduced #dementia risk and modest improvements in cognitive outcomes; no benefit was seen for decaffeinated coffee in an observational study of US adults. https://t.co/jlPgjAuosa https://t.co/RtnibVGs5b Moderate consumption of caffeinated coffee or tea was linked to reduced #dementia risk and modest improvements in cognitive outcomes; no benefit was seen for decaffeinated coffee in an observational study of US adults."
X Link 2026-02-09T18:31Z [----] followers, [----] engagements

"@caloriesproper2 @jerryteixeira @luis_villasenor @DominicDAgosti2 @ProfTimNoakes @The_Wonder_Who @sweatscience @Brady_H @JoseAntonioPhD @nicknorwitz @DoctorTro @NTFabiano @MitoPsychoBio @ChrisPalmerMD @nick_krontiris @luis_villasenor at 12g/kg/day. The pigment changes from hairline down. @caloriesproper2 @jerryteixeira"
X Link 2026-01-21T17:00Z [----] followers, [--] engagements

"@KetoCounselor @zbitter @ProfTimNoakes @drjamesdinic Nicole thank you I appreciate your (incredibly consistent) kindness. No matter how negative the discussion (and it wasn't all negative) I try to take moments to reflect on the validity of the core point being made. The goal is NOT to be right. The goal is to GET it right"
X Link 2026-01-28T12:06Z [----] followers, [---] engagements

"All true and great points. Yet HbA1c remains the strongest predictor of outcomes in diabetes. One can argue this is due to set precedence of the test but this is almot certainly not the case considering plenty of studies look at HR/RR/OR and HbA1c remains in top. Many comparisons when comparing Diabetes as a risk factor compared to other metrics on CVD risk defined diabetes based on a HbA1c so it isnt "diabetes" per say it is the biometric that defines it that is actually what was shown to be linked to those much high risk ratios. -CGMs are more actionable. -Fasting insulin is also incredibly"
X Link 2026-02-10T10:24Z [----] followers, [---] engagements

"@drterrysimpson @DrRogerHugh While I dont always agree wity @drterrysimpson 90% of the obesity epidemic seemed to be explained by diet (and the remains 10% is not necessarily a lack of exercise). Diet must be addressed in weightloss. GLP1Ra directly addressed hunger - diet. https://www.pnas.org/doi/10.1073/pnas.2420902122 https://www.pnas.org/doi/10.1073/pnas.2420902122"
X Link 2026-02-11T13:54Z [----] followers, [--] engagements

"@mcuban Well it was a curl in the squat rack. First mistake"
X Link 2026-02-13T17:23Z [----] followers, [---] engagements

"Inspired by @luis_villasenor"
X Link 2026-02-06T20:13Z [----] followers, [---] engagements

"This is insane and amazing Sub-six-minute mile pace uphill on skis: #WinterOlympics SPEED. 🔥 https://t.co/trof9rs4zf Sub-six-minute mile pace uphill on skis: #WinterOlympics SPEED. 🔥 https://t.co/trof9rs4zf"
X Link 2026-02-10T22:31Z [----] followers, [----] engagements

"But what about if @zbitter or @MountainRoche ran straight to the moon How Long Would It Take to Reach the Moon in a Straight Line https://t.co/jVDsSUh7F3 How Long Would It Take to Reach the Moon in a Straight Line https://t.co/jVDsSUh7F3"
X Link 2026-02-11T18:20Z [----] followers, [---] engagements

"If you are interested in having your questions answered directly consider attending. The recent Training Science Podcast episode with Dr. @AKoutnik sparked strong reactions. Instead of debating in comments were hosting a live moderated Q&A inside our HIIT Science Community. Not a debate. Not position-defending. Clarity. Join us 👇 https://t.co/x8ZjMGbVOD The recent Training Science Podcast episode with Dr. @AKoutnik sparked strong reactions. Instead of debating in comments were hosting a live moderated Q&A inside our HIIT Science Community. Not a debate. Not position-defending. Clarity. Join"
X Link 2026-02-13T19:26Z [----] followers, [----] engagements

"RT @PaulBLaursen: Please join @AKoutnik and me to discuss findings from his team's recent paper (@ProfTimNoakes et al. 2026; Endocrine Rev"
X Link 2026-02-14T18:58Z [----] followers, [--] engagements

"RT @ProfTimNoakes: That's really interesting. We just present our interpretation of the evidence that we worked on for [--] years covering a"
X Link 2026-02-15T15:53Z [----] followers, [--] engagements

"That's really interesting. We just present our interpretation of the evidence that we worked on for [--] years covering a century of published science. I'm guessing that a majority of those who mock individual scientists have probably never read a single scientific paper in their lives. But I guess if you can't follow logic the only way out is to attack the author(s). But some of us live in a world in which the facts actually do matter. @PhilipPrins11 @AKoutnik @LoreofRunning1 In recent days you will have seen dozens of videos talking about it. Some criticizing the study and mocking Noakes;"
X Link 2026-02-15T15:05Z 157.9K followers, [----] engagements

"In recent days you will have seen dozens of videos talking about it. Some criticizing the study and mocking Noakes; others saying the opposite. I think the easy reaction here is to believe that one side is completely right and the other half are idiots or frauds"
X Link 2026-02-14T13:05Z [----] followers, [----] engagements

"Please join @AKoutnik and me to discuss findings from his team's recent paper (@ProfTimNoakes et al. 2026; Endocrine Reviews) and its fuelling practice implications across individuals. All welcome @LoreofRunning1. The recent Training Science Podcast episode with Dr. @AKoutnik sparked strong reactions. Instead of debating in comments were hosting a live moderated Q&A inside our HIIT Science Community. Not a debate. Not position-defending. Clarity. Join us 👇 https://t.co/x8ZjMGbVOD The recent Training Science Podcast episode with Dr. @AKoutnik sparked strong reactions. Instead of debating in"
X Link 2026-02-14T03:41Z 10K followers, [----] engagements

"The recent Training Science Podcast episode with Dr. @AKoutnik sparked strong reactions. Instead of debating in comments were hosting a live moderated Q&A inside our HIIT Science Community. Not a debate. Not position-defending. Clarity. Join us 👇 https://www.skool.com/hiit-science https://www.skool.com/hiit-science"
X Link 2026-02-13T18:27Z 42.5K followers, [----] engagements

"Two athletes. Same VO2max. Same workout. Athlete 1: Burns mostly carbs Finishes empty Needs [--] hrs to recover Athlete 2: Burns more fat + fuels during the session Finishes with glycogen left Recovers in hours How quickly you recover isnt just fitness age or genetics. Its fueling strategy + metabolic flexibility🔥"
X Link 2026-02-11T19:44Z 57.3K followers, 44.6K engagements

"How Long Would It Take to Reach the Moon in a Straight Line"
X Link 2026-02-10T22:39Z 1.5M followers, 2.6M engagements

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