@ewelin34 ewelin34
ewelin34 posts on Reddit about university of, has been, $4507t, cure for the most. They currently have [---] followers and [--] posts still getting attention that total [---] engagements in the last [--] hours.
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- [--] Months [-----] +601%
- [--] Year [-----] +934%
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- [--] Week [--] +9.10%
- [--] Month [--] -6.70%
- [--] Months [--] +40%
- [--] Year [--] +84%
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- [--] Months [---] +8.20%
- [--] Year [---] +69%
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Social Influence
Social category influence countries 4.3% finance 3.23% social networks 2.15% travel destinations 2.15% fashion brands 1.08% technology brands 1.08%
Social topic influence university of 8.6%, has been 5.38%, $4507t #13, cure for 3.23%, community 2.15%, rescue 2.15%, twitch 2.15%, edinburgh 2.15%, in a 2.15%, compound 2.15%
Top accounts mentioned or mentioned by @kuedumailtofragilexlab @kuedulearn
Top assets mentioned Frontier (FRONT)
Top Social Posts
Top posts by engagements in the last [--] hours
"Today Shionogi announced significant progress in their efforts to develop the investigational new drug Zatolmilast (BPN14770) to treat Fragile X syndrome (FXS). FragileXReseach FragileXReseach"
Reddit Link 2025-02-06T14:06Z [--] followers, [--] engagements
"NPR Highlights Life-Changing Fragile X Breakthrough Hear Jasons Story FragileXReseach FragileXReseach"
Reddit Link 2024-10-30T00:12Z [--] followers, [--] engagements
"Shionogis Fragile X Clinical Trials Near Completion Adult Enrollment Closed Adolescent Trial in Final Phase FragileXReseach FragileXReseach"
Reddit Link 2025-09-07T14:07Z [--] followers, [--] engagements
"Changes are happening with the Zatolmilast clinical trials for Fragile X syndrome. FragileXReseach FragileXReseach"
Reddit Link 2025-02-04T18:26Z [--] followers, [--] engagements
"PDE Inhibitors Show Promise for Treating Fragile X Syndrome and Other Brain Disorders FragileXReseach FragileXReseach"
Reddit Link 2025-03-26T17:46Z [--] followers, [--] engagements
"RECONNECT Trial Results: ZYN002 Does Not Meet Primary Endpoint in Fragile X FragileXReseach FragileXReseach"
Reddit Link 2025-09-26T08:28Z [--] followers, [--] engagements
"Whats next for the Shionogi EXPERIENCE trials FragileXReseach FragileXReseach"
Reddit Link 2025-04-01T20:38Z [--] followers, [--] engagements
"Progress update on ZYN002 for Fragile X syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-05-06T14:19Z [--] followers, [--] engagements
"Clinical trial milestone: Zatolmilast study in Fragile X syndrome now fully enrolled FragileXReseach FragileXReseach"
Reddit Link 2025-06-17T17:52Z [--] followers, [--] engagements
"Shionogi Shares Update on Zatolmilast Fragile X Clinical Trials FragileXReseach FragileXReseach"
Reddit Link 2025-10-27T16:12Z [--] followers, [--] engagements
"Pharmacological Activation of PGC-1 to Treat Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-12-22T16:36Z [--] followers, [--] engagements
"Centers for Collaborative Research in Fragile X Receive $25 Million Over Next [--] Years FragileXReseach FragileXReseach"
Reddit Link 2026-02-10T18:23Z [--] followers, [--] engagements
"Dr. Tranfaglia & Katie Clapp recently spoke at Shionogi's employee Town Hall shedding light on Fragile X. Shionogi along with Tetra Therapeutics are working diligently to develop Zatolmilast a new investigational drug for Fragile X treatment. The Phase [--] clinical trials are currently happening. FragileXReseach FragileXReseach"
Reddit Link 2025-02-06T14:06Z [--] followers, [--] engagements
"Time Sensitive: Zatolmilast Trials Clarification with FX Community FragileXReseach FragileXReseach"
Reddit Link 2024-11-15T16:39Z [--] followers, [--] engagements
"PDE4 and PDE2 inhibitors explored as therapeutic options for Fragile X syndrome and beyond biotech biotech"
Reddit Link 2025-03-26T17:56Z [--] followers, [--] engagements
"Callum Cup IX Brings Community Together Raising $19500 for Fragile X Research FragileXReseach FragileXReseach"
Reddit Link 2025-12-17T20:45Z [--] followers, [--] engagements
"METTL3 Inhibitors and FDA-Approved Drugs in a New Fragile X Treatment Strategy Using Organoids FragileXReseach FragileXReseach"
Reddit Link 2025-11-04T18:10Z [--] followers, [--] engagements
"Mirum Launches Clinical Trial of MRM-3379 for Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-12-01T18:33Z [--] followers, [--] engagements
"BK Channel Openers: A New Hope for Fragile X Treatment Insights from Kaerus Bioscience CEO Robert Ring The latest advances in Fragile X syndrome research are moving us closer to impactful treatments. Rob Ring CEO of Kaerus Bioscience is at the forefront collaborating with FRAXA to develop BK channel openersan innovative therapeutic approach targeting the core challenges of Fragile X. These developments have the potential to not only address symptoms of Fragile X but also to impact the broader neurodevelopmental disorder landscape including autism. With FRAXA's continued support in"
Reddit Link 2024-10-22T14:46Z [---] followers, [--] engagements
"Metabolic and Mitochondrial Crosstalk in Insulin and cAMP Pathways in Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-08-28T14:54Z [--] followers, [--] engagements
"Servier acquires potential treatment for Fragile X syndrome the most common genetic cause of autism spectrum disorder FragileXReseach FragileXReseach"
Reddit Link 2025-09-08T21:28Z [--] followers, [--] engagements
"Fragile X Syndrome: What Happens in the Brain FragileXReseach FragileXReseach"
Reddit Link 2025-09-09T16:08Z [--] followers, [--] engagements
"BK Channel Openers: From FRAXA Seed Funding to Big Pharma Investment and Trials FragileXReseach FragileXReseach"
Reddit Link 2025-09-11T18:35Z [--] followers, [--] engagements
"ASO Rescue of FMR1 Mis-Splicing in Neurons and Mitigation of Fragile X Deficits FragileXReseach FragileXReseach"
Reddit Link 2025-09-16T16:49Z [--] followers, [--] engagements
"Validate a Novel Antisense Oligonucleotide Therapeutic for Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-09-19T22:23Z [--] followers, [--] engagements
"FMRP Regulatory Role in Human Hippocampal Development and Therapeutic Interventions in Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-10-16T17:38Z [--] followers, [--] engagements
"Gene Therapeutic Development for Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-10-28T17:33Z [--] followers, [--] engagements
"Celebrating [--] Years of the Fragile X Poker Run in Sparta NC FragileXReseach FragileXReseach"
Reddit Link 2025-10-30T17:46Z [--] followers, [--] engagements
"Pokmon Tournament Twitch Stream Raises $2100 for FRAXA FragileXReseach FragileXReseach"
Reddit Link 2025-11-05T21:15Z [--] followers, [--] engagements
"Cell Type-Specific Protein Dysregulation in Fragile X Syndrome Brain Organoids FragileXReseach FragileXReseach"
Reddit Link 2025-11-10T18:08Z [--] followers, [--] engagements
"Identifying New Therapeutic Approaches Using a Human Fragile X Model FragileXReseach FragileXReseach"
Reddit Link 2025-11-12T20:34Z [--] followers, [--] engagements
"Exploring the Auditory System Therapeutic Target for Fragile X Syndrome FragileXReseach FragileXReseach"
Reddit Link 2025-11-20T19:30Z [--] followers, [--] engagements
"This GivingTuesday our community reminded us what hope in action looks like. FragileXReseach FragileXReseach"
Reddit Link 2025-12-03T18:36Z [--] followers, [--] engagements
"Advanced Preclinical Testing of NKCC1 Inhibitors Supporting Phase [--] Trials in Fragile X FragileXReseach FragileXReseach"
Reddit Link 2025-12-04T16:32Z [--] followers, [--] engagements
"Uncovering the Dynamics of FMR1 Using Spatial Transcriptomics for Fragile X FragileXReseach FragileXReseach"
Reddit Link 2025-12-12T17:04Z [--] followers, [--] engagements
"Call for Proposals: Fragile X Research Funding (Deadline Feb 2) FragileXReseach FragileXReseach"
Reddit Link 2025-12-15T18:21Z [--] followers, [--] engagements
"Dr. Zhexing Wen and Dr. Peng Jin of the newly funded Fragile X Center of Excellence at Emory University School of Medicine join us in this seminar to present Towards Understanding the Role of FMRP in Human Brain Development Using Brain Organoids. FragileXReseach FragileXReseach"
Reddit Link 2024-11-19T11:19Z [--] followers, [--] engagements
"Fragile X syndrome and Cancer Research: Unexpected Links and Opportunities for Collaboration - Uncover the surprising connections between Fragile X syndrome and cancer and how these links could lead to advances in treatment and research for both patient communities"
Reddit Link 2023-04-11T14:34Z [--] followers, [---] engagements
"Allos Pharma Inc. is making significant progress in Fragile X research. After a constructive meeting with the FDA the company is enhancing their planned pivotal Phase [--] clinical trial design offering renewed hope for an approved drug to treat this disorder. FragileXReseach FragileXReseach"
Reddit Link 2023-05-24T18:08Z [---] followers, [--] engagements
"Awarded a FRAXA Research grant Dr. Andrew Stanfield Dr. Leena Williams & Dr. Damien Wright are set to explore somatosensory processing (sense of touch) in Fragile X syndrome at the University of Edinburgh. Their aim A noninvasive touch test that could set the stage for future clinical trials"
Reddit Link 2023-09-07T20:54Z [--] followers, [---] engagements
"Grateful to the Fragile X community for funding another FRAXA research grant. The Smith lab is studying a potential new approach using Saracatinib to aid in Fragile X syndrome treatment"
Reddit Link 2023-09-15T17:16Z [--] followers, [--] engagements
"Research Opportunity for women [--] - [--] with and without the premutation of the FMR1 gene"
Reddit Link 2023-10-02T16:32Z [--] followers, [---] engagements
"please join FRAXA co-founders Katie Clapp and Dr. Michael Tranfaglia for a Research Q&A on Wednesday November [--] [----] at 12:00 pm (noon) ET"
Reddit Link 2023-11-02T17:25Z [--] followers, [---] engagements
"Imagine a future where Sulies son enjoys life beyond the limitations of Fragile X. We're close to key research advances. Your support can unlock a brighter future for families like Sulie's"
Reddit Link 2023-12-09T16:32Z [--] followers, [---] engagements
"Inside the FRAXA Drug Validation Initiative: Advancing Fragile X Treatments Discover the FRAXA Drug Validation Initiative (FRAXA-DVI) led by Dr. Patricia Cogram at the University of Chile. Since [----] FRAXA-DVI has been a piece of Fragile X drug development pipeline testing hundreds of potential treatments. Highlights include the promising outcomes of Tetra Therapeutics' zatolmilast which is now in phase [--] clinical trials. FRAXA-DVI is a essential element in the pursuit of effective treatments and a cure for Fragile X. Explore the World of FRAXA-DVI:"
Reddit Link 2024-03-13T15:41Z [---] followers, [--] engagements
"Renewed Hope: Navigating Towards a Cure for Fragile X Syndrome Dr. Peter Todd professor at the University of Michigan explains his pragmatic optimism about finding a cure for Fragile X syndrome. We are in a much more mature space these days. Now there is aninflux of top biological companies willing to invest millions of dollars to develop advanced treatments and eventually a cure. Join us in supporting these crucial efforts. Read Article:"
Reddit Link 2024-04-16T18:38Z [--] followers, [--] engagements
"FDA has approved Spinogenix's Investigational New Drug (IND) application The FDA has approved Spinogenix's Investigational New Drug (IND) application for their compound SPG601 which is now ready for Phase 2a trials as a potential treatment for Fragile X syndrome (FXS). Dr. Craig Erickson remarks "We look forward to the first study of a BK channel modulator in humans with Fragile X and taking the first step to evaluate this important drug mechanism in Fragile X Syndrome." BK channel openers were proposed to treat Fragile X years ago by a French"
Reddit Link 2024-04-22T15:25Z [---] followers, [--] engagements
"Online survey to collect views on the potential use of gene therapy in treating Fragile X syndrome The Patrick Wild Centre is conducting an online survey to collect views on the potential use of gene therapy in treating Fragile X syndrome (FXS). This approach which targets the genetic factors underlying FXS is being explored as there are currently no treatments available that address the genetic cause of the condition. Gene therapy has demonstrated potential in laboratory studies and is being considered for other genetic neurodevelopmental disorders. The survey aims to understand the"
Reddit Link 2024-05-08T14:06Z [---] followers, [--] engagements
"Fragile X Treatment Target Emerges from Neurolixis & FRAXA Collaboration A new treatment target for Fragile X syndrome has emerged: serotonin 1A. Neurolixis a FRAXA pharma partner has announced their Fragile X syndrome development program for their investigational new drug NLX-101 which targets the 5-HT1A serotonin receptor. This selective drug has potential to reduce anxiety improve learning and reduce seizures in Fragile X individuals with minimal side effects. Multiple studies funded by FRAXA have pointed to serotonin 1A. Dr. Khaleel Razaks team at UC Riverside Dr. Clinton Canal's team at"
Reddit Link 2024-06-24T18:04Z [---] followers, [--] engagements
"QurAlis and UMass Chan Advance Fragile X Syndrome Treatment using ASOs (Antisense Oligonucleotides) QurAlis Corporation and UMass Chan Medical School have partnered to develop potential therapies using antisense oligonucleotide (ASO) splicing technology. This collaboration builds on groundbreaking research by Dr. Joel Richter and his team at UMass funded by FRAXA Research Foundation. Their discovery revealed that the FMR1 gene in individuals with Fragile X syndrome isn't entirely inactive but produces a mis-spliced messenger RNA. With an ASO they aim to neutralize this deviant RNA potentially"
Reddit Link 2024-06-25T20:48Z [---] followers, [--] engagements
"Potential Changes Ahead for NICHD The House Appropriations Committee has proposed combining NICHD with NIDCD into a new National Institute for Disability Related Research in their FY25 bill. This proposal is still in its early stages and subject to change. Stay informed and learn more about this proposal: Watch the Subcommittee Markup:https://appropriations.house.gov/events/markups/subcommittee-markup-fy25-labor-health-and-human-services-education-and-related(https://appropriations.house.gov/events/markups/subcommittee-markup-fy25-labor-health-and-human-services-education-and-related) Read"
Reddit Link 2024-06-26T16:50Z [---] followers, [--] engagements
"Kaerus Bioscience has initiated a Phase [--] clinical trial for KER-0193 Kaerus Bioscience has initiated a Phase [--] clinical trial for KER-0193 a novel BK channel modulator developed for Fragile X syndrome in Belgium. After over [--] years of R&D supported by partnerships with academic collaborators and FRAXA this trial marks a significant milestone. KER-0193 has shown promising preclinical results in improving behavioral sensory and cognitive functions. FRAXA is proud to have been part of this journey and we look forward to seeing the outcomes of this clinical trial."
Reddit Link 2024-07-25T18:49Z [---] followers, [--] engagements
"Understanding Anxiety in Fragile X Syndrome: Insights from Dr. Carrie Buchanan's Webinar Discover invaluable insights on managing anxiety in individuals with Fragile X syndrome from our recent World Fragile X Day webinar. Dr. Carrie Buchanan Fragile X Program Director at Greenwood Genetic Center delves into the neurobiological reasons behind anxiety common anxiety behaviors and practical strategies to enhance the quality of life for children and adults with Fragile X. Understand the role of the amygdala non-medication treatments and medication options in this informative session."
Reddit Link 2024-08-01T17:23Z [---] followers, [--] engagements
"World Fragile X Day 2024: A Global Celebration of Awareness and Research Progress 🌍 On July [--] [----] World Fragile X Day(https://www.fraxa.org/world-fragile-x-day-2024-a-global-celebration-of-awareness-and-research-progress/) brought together [--] countries in a remarkable display of global unity and awareness. From Niagara Falls to Matagarup Bridge over [---] landmarks around the world were illuminated to symbolize hope and solidarity for those affected by Fragile X syndrome. As we look back on this impactful day we're reminded of the power of global collaboration in raising awareness and"
Reddit Link 2024-08-12T15:31Z [---] followers, [--] engagements
"Marvel Biosciences Partners with FRAXA to Test MB204 for Fragile X Syndrome FRAXA Research Foundation is working together with Marvel Biosciences Corporation in an exciting new preclinical study examining the effects of Marvels MB204 drug. FRAXAs collaboration with Marvel Biosciences exemplifies FRAXA's strategy of feeding new treatment ideas into the development pipeline. By funding high-quality academic studies with a therapeutic focus and partnering with innovative companies like Marvel FRAXA accelerates the development of promising new treatments for Fragile X syndrome.#FragileX"
Reddit Link 2024-08-20T18:40Z [---] followers, [--] engagements
"Fragile X Unplugged: Establishing Mobile EEG as the Next Frontier FRAXA is proud to announce a $100000 research grant(https://www.fraxa.org/fragile-x-unplugged-establishing-mobile-eeg-as-the-next-frontier/) awarded to Dr. Craig Erickson Dr. Lisa De Stefano and Dr. Lauren Schmitt at Cincinnati Children's Hospital. This grant aims to transform clinical trials in Fragile X syndrome by simplifying and adapting EEG technology for home use. By enabling clinicians to administer EEG tests in patients' homes this project could significantly improve the efficiency and accessibility of future trials."
Reddit Link 2024-08-22T16:23Z [---] followers, [--] engagements
"Gene Editing of FMR1 to Correct FXS Phenotypes in Mice FRAXA is pleased to announce a $100000 research grant(https://www.fraxa.org/gene-editing-of-fmr1-to-correct-fxs-phenotypes-in-mice/) to Dr. Beverly Davidson and Dr. Carolyn Yrigollen at Childrens Hospital of Philadelphia. The team aims to optimize state-of-the-art gene editing tools to treat Fragile X syndrome. They will test these tools in a unique mouse model to see if they can correct FMR1 mutations. This research will advance our understanding of how to use gene editing to treat Fragile X syndrome and its made possible by the"
Reddit Link 2024-09-05T20:10Z [---] followers, [--] engagements
"Investigating and Correcting the Mechanistic Basis of Altered Physiology of Primary Visual Cortex in Fragile X Syndrome FRAXA is proud to continue our long-standing support for Picower Professor Dr. Mark Bear and his team at the Massachusetts Institute of Technology. With a $100000 grant from FRAXA(https://www.fraxa.org/altered-physiology-of-primary-visual-cortex-in-fragile-x-syndrome/) Dr. Bear and Postdoctoral Fellow Dr. Sara Kornfeld Simpson will test their hypothesis that certain inhibitory neurons in the brain are impaired in Fragile X syndrome -- and that stimulating these neurons can"
Reddit Link 2024-09-19T15:35Z [---] followers, [--] engagements
"Research Opportunity through the Fragile X lab at the University of Kansas https://preview.redd.it/x4ye0kisyzpd1.pngwidth=1864&format=png&auto=webp&s=16e307c85f3fb2e18db3c4752f0aa8d8b754bb62 You and your young adult (18 - 22) with Fragile X areinvited to join a research study with the Fragile X Lab at the University of Kansas LifeSpan Institute. Their team will travel to your home anywhere in the United States at yourconvenience. Participants will be compensated for their time.Whats involved: * Surveys * Language Assessment * Interviews * Mother & Child Activity Your participation will help"
Reddit Link 2024-09-20T17:14Z [---] followers, [--] engagements
"NPR's Morning Edition has scheduled a story on FRAXA. Monday September [--] NPR's Morning Edition has scheduled a story on FRAXA highlighting the progress of research aimed at Fragile X treatments. The segment will include a special feature on the Mazzola family's personal journey and experience with Zatolmilast an investigational new drug currently in late stage clinical trials. Be sure to tune in **Please note if theres a major news story the segment may get bumped to another day but were hopeful it will air as planned"
Reddit Link 2024-09-20T17:15Z [---] followers, [--] engagements
"Attention Fragile X caregivers and patients in the US Help complete a 60-minute web-assisted phone interview"
Reddit Link 2024-09-28T13:48Z [---] followers, [--] engagements
"Big Congratulations to FRAXA Investigator Dr. Lynne E. Maquat 🎉 Congratulations to FRAXA Investigator Dr. Lynne Maquat recipient of the [----] Dr. Paul Janssen Award 🏆 Her research on nonsense-mediated mRNA decay (NMD) is crucial in understanding RNA decay in cancer genetic disorders and Fragile X. FRAXA is proud to support her work. https://www.urmc.rochester.edu/news/story/lynne-maquat-receives-2024-dr-paul-janssen-award(https://www.urmc.rochester.edu/news/story/lynne-maquat-receives-2024-dr-paul-janssen-award) FragileXReseach FragileXReseach"
Reddit Link 2024-10-08T13:54Z [--] followers, [--] engagements
"A second award for Dr. Maquat "If I had any advice for young scientists: utilize your strength. We all have weaknesses. Compensate for those weaknesses and once you define them and if you keep chipping away ." Dr. Lynne Maquat FRAXA has been funding Dr. Maquat's research on Fragile X since [----]. Her groundbreaking work on RNA biology has advanced our understanding of Fragile X syndrome. She was just honored with the [----] Albany Medical Center Prize in Medicine and Biomedical Research; only [--] weeks ago she also received the Dr. Paul Janssen Award for Biomedical Research. Lets keep pushing the"
Reddit Link 2024-10-18T16:54Z [--] followers, [--] engagements
"Join us virtually on December [--] at 12:00 pm ET for Fragile X Family Conversations: Sharing Learning Supporting. Calling all families navigating the Fragile X journey Join us virtually on December [--] at 12:00 pm ET for Fragile X Family Conversations: Sharing Learning Supporting(https://www.fraxa.org/events/fragile-x-family-conversations-sharing-learning-supporting-2024-12/). This exclusive event is a space just for families and caregivers to connect share experiences and offer each other support. These sessions provide unique opportunities to brainstorm with others who truly understand the"
Reddit Link 2024-11-08T17:08Z [---] followers, [--] engagements
"Kicking Off Our [----] Giving Season With Gratitude and Hope As we kick off FRAXA's [----] Annual Appeal we are humbled by a $100000 gift from the Berg and Schatz families honoring young Cooper who lives with Fragile X syndrome. Their generosity will enable FRAXA to fund two new research teams next springpropelling us closer to treatments and one day a cure. This donation is a powerful reminder of the resilience and hope that define families impacted by Fragile X. Together with every donation we are making strides in advancing research that holds the potential to change lives. We invite you to"
Reddit Link 2024-11-14T17:14Z [---] followers, [--] engagements
"Help Us Transform Lives with Fragile X Research For [--] years Jason Mazzolas life was shaped by the challenges of Fragile X syndrome severe anxiety communication difficulties and constant supervision. But in [----] everything changed. After completing a double-blind clinical trial Jason began taking zatolmilast as part of an open label extension. His world opened up. Now he walks downtown by himself gets his haircut on his own and even holds a job. His mother Lizzie shared He wouldnt have done any of this before. This is why FRAXA is committed to advancing research that changes lives. With"
Reddit Link 2024-11-20T17:04Z [---] followers, [--] engagements
"Dr. Jeannie Lee's Innovative Fragile X Gene Therapy Research Gets a Boost from SFARI Harvard Medical School investigator Jeannie Lee MD PhD has won a grant from SFARI (The Simons Foundation) to advance her work on reactivating the mutated gene responsible for Fragile X syndrome. With prior FRAXA funding Dr. Lee discovered how "R-loops" can shrink this mutationa promising approach to gene reactivation. This new support from SFARI will further propel these advances."
Reddit Link 2024-11-22T17:31Z [---] followers, [--] engagements
"GEXVal and FRAXA Collaborate to Advance Fragile X Research with Phase 2a Trial GEXVal Inc. a collaborator of FRAXA Research Foundation is developing an investigational new drug for Fragile X syndrome. Their Phase 2a Proof of Concept trial for GXV-001 has been selected for the Japan Agency for Medical Research and Developments Strengthening Program for Pharmaceutical Startup Ecosystem. This critical funding will advance the global trial of GXV-001. The compound has already been tested extensively at FRAXAs Drug Validation Initiative (FRAXA-DVI) a preclinical testing resource dedicated to"
Reddit Link 2025-01-02T16:09Z [---] followers, [--] engagements
"FRAXA Launches Bold [----] Initiative to Fund Curative Therapies for Fragile X Researchers Invited to Apply In [----] FRAXA is taking a bold step toward a cure for Fragile X syndrome with a new grant program focused on curative therapies. This initiative supports groundbreaking approaches such as gene therapy gene repair protein replacement mRNA therapeutics and targeted ASO treatments. Researchers are invited to apply for funding of up to $100000 per year. Lets drive meaningful advances in Fragile X therapeutics and deliver life-changing solutions to Fragile X families."
Reddit Link 2025-01-14T15:53Z [---] followers, [--] engagements
"FRAXA-Funded Research Explores ISRIB as a Potential Treatment for Fragile X FRAXA-funded researchers at Stanford University have been investigating how ISRIB(https://www.fraxa.org/fraxa-funded-research-explores-isrib-as-a-potential-treatment-for-fragile-x/) an experimental drug might help restore brain function and social behavior in Fragile X syndrome. In Fragile X neurons struggle to regulate protein production leading to disrupted learning memory and communication between brain cells. This study found that ISRIB: Reduced the number of immature dendritic spines improving brain"
Reddit Link 2025-02-26T17:32Z [---] followers, [--] engagements
"Rare Disease Day: Pushing Forward in Fragile X Research Today on Rare Disease Day we celebrate the millions of individuals and families affected by Fragile X syndrome and other rare disorders. Progress is happening every day Pivotal clinical trials of new treatments are moving closer to completion. Behind the scenes FRAXA is reviewing a exciting batch of new Fragile X research proposals with new awards to be announced in early April. And other companies are working to develop even better treatments. Together we keep moving forward. FragileXReseach FragileXReseach"
Reddit Link 2025-02-28T16:39Z [---] followers, [--] engagements
"Fragile X Family Conversations: Sharing Learning Supporting (April [--] 2025) Calling all families navigating the Fragile X journey Join us on April [--] at 12:00 pm ET for Fragile X Family Conversations a dedicated space for families and caregivers to connect share experiences and support one another. These virtual meetups have been incredibly valuable in bringing families together and weve truly enjoyed each one. They provide a unique opportunity to exchange ideas with others who understand the challenges of Fragile X. As Fragile X parents ourselves the FRAXA team fosters a welcoming space"
Reddit Link 2025-03-05T17:06Z [---] followers, [--] engagements
"Advancing Curative Therapy for Fragile X Syndrome: Turner Lab Secures $1M Grant Another big step toward curative therapy for Fragile X syndrome With funding from FRAXA Dr. Raymond Turners team at the University of Calgary has been working to replace FMRP the missing protein in Fragile X using a targeted protein therapy. Their innovative Tat-FMRP approach has shown promising results restoring brain function in mice and reducing hyperactivity. Now their progress is accelerating. Their work has secured a $1 million grant from the Canadian Institutes of Health Research (CIHR) to expand and refine"
Reddit Link 2025-03-10T15:55Z [---] followers, [--] engagements
"🚨 NIH funding delays are putting Fragile X research at risk Fragile X syndrome research is at a critical turning point but without funding progress may grind to a halt. The Centers for Collaborative Research in Fragile X which drive key discoveries face uncertainty. Researchers are left in limbo unable to continue promising studies that could lead to new treatments and a cure. FRAXA Research Foundation and the National Fragile X Foundation are working together to urge Congress and the NIH to act now. Funding delays dont just slow sciencethey set research back for years. The Fragile X"
Reddit Link 2025-03-13T20:04Z [---] followers, [--] engagements
"Zatolmilast: A potential treatment for Fragile X now being tested in Jordans syndrome The scope of research on zatolmilast (BPN14770) is expanding now reaching another neurodevelopmental disorderJordans syndrome. With a new phase [--] clinical trial underway this adds yet another iron in the fire strengthening the path toward a potential treatment. Zatolmilast has already shown promise in Fragile X syndrome demonstrating cognitive improvements and meaningful functional gains in previous trials. Now as it is being explored in Jordans syndrome we remain hopeful that this research will help advance"
Reddit Link 2025-04-01T16:42Z [---] followers, [--] engagements
"Fragile X and Fatigue: Study Reveals How Muscle Function is Altered in Children A peer-reviewed study funded by FRAXA Research Foundation reveals a shift in how children with Fragile X syndrome recruit muscle fibers during walking. They rely more on fast-twitch fibers which fatigue quickly instead of the more efficient slow-twitch ones. This discovery sheds light on why many individuals with Fragile X experience fatigue and motor challenges. It also expands the clinical understanding of Fragile X syndrome beyond cognition and behavior. The research team based at the University of Padua used"
Reddit Link 2025-04-16T16:59Z [---] followers, [--] engagements
"Together for a Brighter Future: Celebrating the 5th World Fragile X Day World Fragile X Day is more than awareness. It sparks early diagnoses inspires research funding and unites communities across countries and time zones. Every July [--] landmarks around the world light up to honor families affected by Fragile X syndrome. What began five years ago with FRAXA Research Foundation and global partners has become a powerful tradition that has sparked celebrations across [--] countries. Whether you're fundraising hosting an event or helping light up a local landmark your efforts bring us closer to"
Reddit Link 2025-04-17T15:47Z [--] followers, [--] engagements
"New Research Targets NMDA Receptor A Key Player in Brain Communication and Fragile X Syndrome A recently published study from the Picower Institute at MIT supported in its early stages by FRAXA funding shows that fine-tuning NMDA receptor activity can help correct core brain signaling issues in Fragile X syndrome. By targeting a specific NMDA receptor subunit researchers were able to restore normal protein production in mouse models leading to better learning and reduced sensory overload. Research advances like this reflect what is possible with persistence collaboration and community"
Reddit Link 2025-04-30T16:01Z [---] followers, [--] engagements
"Harvards Dr. Jeannie Lee Wins $1M Award to Develop Gene Reactivation Therapy for Fragile X Dr. Jeannie Lee a leading researcher at Harvard Medical School and Massachusetts General Hospital has been awarded a $1 million Blavatnik Therapeutics Challenge Award to expand her innovative work reactivating the gene that fails to function in Fragile X syndrome. This award builds on years of research funded by FRAXA and is one of the most competitive funding programs at Harvard Medical School designed to fast-track promising science toward real-world treatments. It also means that FRAXA can fund the"
Reddit Link 2025-06-02T15:59Z [---] followers, [--] engagements
"What research is FRAXA funding in [----] Join us for a live webinar where FRAXA Co-Founders Dr. Michael Tranfaglia and Katie Clapp will present an overview of all Fragile X research grants awarded so far this year. From novel therapeutic strategies to innovative models of Fragile X syndrome each project represents a step forward in our mission to accelerate effective treatments. Whether youre a scientist clinician or part of the Fragile X community this session offers a comprehensive view of where the field is heading and whos driving it. Learn whats being funded Understand research priorities"
Reddit Link 2025-06-03T19:59Z [---] followers, [--] engagements
"UMass Chan Medical School Licenses RNA-Based Therapy to QurAlis Advancing a New Era in Fragile X Treatment UMass Chan Medical School has officially licensed a promising RNA-based therapeutic technology to QurAlis aiming to correct the root cause of Fragile X syndromenot just manage symptoms. This work builds on discoveries from Drs. Joel Richter and Sneha Shah supported by FRAXA that revealed the FMR1 gene isnt usually silent in Fragile X. Instead a mis-spliced RNA message FMR1-217 disrupts protein production. QurAlis is now developing antisense oligonucleotide (ASO) therapy to fix this error"
Reddit Link 2025-06-05T17:03Z [---] followers, [--] engagements
"Fragile X families you're not alone. 💙 Join us on Tuesday June [--] at 12:00 pm ET for our next Fragile X Family Conversations a welcoming space just for families and caregivers to connect share and support one another. These small-group virtual sessions are led by the FRAXA team all parents of loved ones with Fragile X and provide a chance to talk with others who truly understand the journey. Lets brainstorm listen and lift each other up. Space is limited reserve your spot now FragileXReseach FragileXReseach"
Reddit Link 2025-06-10T16:43Z [---] followers, [--] engagements
"Modeling R-Loop Therapy for Fragile X Syndrome in Patient-Derived Brain Organoids Dr. Jeannie Lees groundbreaking project aims to reactivate the silenced FMR1 gene in Fragile X syndrome using a novel R-loop gene-editing approach. Early studies in human patient-derived neurons demonstrated robust FMR1 reactivation. Now a $100000 award from the FRAXA Curative Therapies Fund co-funded with the Pierce Family Fragile X Foundation will move this work into 3-dimensional brain organoids to test functional rescue. By precisely removing the CGG repeat expansion the team seeks to restore FMR1"
Reddit Link 2025-06-19T15:09Z [---] followers, [--] engagements
"Role of Microglia in Fragile X Syndrome We are pleased to partner with the Autism Science Foundation to award $35000 to Dr. Marine Anais Krzisch at the University of Leeds for her project exploring microglia in Fragile X syndrome. Dr. Krzisch will study how Fragile X microglia behave in a living brain and hopefully uncover new pathways to treatment. By using a human iPSC-based model to examine synaptic pruning and inflammatory responses this research advances our understanding of key mechanisms in Fragile X syndrome and related neurodevelopmental disorders. We are deeply grateful to our"
Reddit Link 2025-06-26T14:45Z [--] followers, [--] engagements
"Fragile X Syndrome Research in 2025: FRAXA Announces New Grants & Promising Leads What does real progress in Fragile X syndrome research look like In our [----] Research Grants Webinar FRAXA Co-Founders Dr. Mike Tranfaglia and Katie Clapp walk through [--] newly funded projects from gene reactivation and ASO therapy to personalized organoid models and preclinical drug testing tools. These grants reflect a focused push toward curative therapies and better clinical options. They also show how researchers around the world are collaborating across disciplines to accelerate impact. Were grateful"
Reddit Link 2025-07-16T17:18Z [--] followers, [--] engagements
"Why does Fragile X syndrome affect males and females differently and can targeting estrogen receptors help balance those effects This research explores why Fragile X can impact males and females differently focusing on how estrogen may influence sensory circuit dysfunction in the brain. Dr. Kimberly Huber and Dr. Nadine Nijem at UT Southwestern are testing whether FDA-approved drugs that target estrogen can reduce brain hyperexcitability and seizures in Fragile X mice. The team is paving the way toward sex-specific treatment strategies a critical step toward personalized care. FRAXA is proud"
Reddit Link 2025-07-29T17:24Z [--] followers, [--] engagements
"Medication Guide for Fragile X Syndrome Were proud to share the newly updated Fragile X Medication Guide (Version [--] 2025)(https://www.fraxa.org/medication-guide-for-fragile-x-syndrome/) a freely available resource offered as a gift to the community. Authored by FRAXAs Medical Director Dr. Michael Tranfaglia this guide was created to help parents and caregivers navigate medication options for the behavioral and psychiatric symptoms of Fragile X syndrome. The guide is clear practical and written in plain language designed to support more informed collaborative conversations with healthcare"
Reddit Link 2025-08-07T15:08Z [--] followers, [--] engagements
"Oligodendrocytes: a Potential Route to Treat Fragile X Syndrome FRAXA Research Foundation has awarded $100000 to support a two-year study at the University of Edinburgh Scotland investigating an often-overlooked aspect of Fragile X syndrome: the role of oligodendrocytes brain support cells responsible for producing myelin. Led by Dr. Lida Zoupi and FRAXA Postdoctoral Fellow Dr. Laura Oliveira this research will test whether deficits in these cells contribute to the brain communication challenges seen in Fragile X syndrome and explore if restoring their function can improve brain activity. By"
Reddit Link 2025-08-15T18:34Z [--] followers, [--] engagements
"Patricks PALS [--] Raises Over $150K for Fragile X Syndrome at 3-on-3 Tournament Nearly three decades of basketball community and commitment came together at Patricks PALS 29th Annual 3-on-3 Basketball Tournament raising over $150000 to support Fragile X research. What began as a small group of friends rallying around a cause in [----] has grown into an extraordinary tradition that fuels FRAXA Research Foundations mission to accelerate progress toward effective treatments and ultimately a cure for Fragile X syndrome. The event celebrated both competition and compassion: 🏀 Inspiring athletes on"
Reddit Link 2025-08-21T13:45Z [--] followers, [--] engagements
"Evaluating Novel Drug Candidates for Fragile X Syndrome Using the Live Mouse Tracker Researchers at the University of Antwerp are harnessing artificial intelligence and advanced mouse behavior tracking to identify potential new treatments for Fragile X syndrome. Using the Live Mouse Tracker the team can monitor dozens of behaviors in mice over [--] hours providing a standardized and scalable way to evaluate drug candidates. This approach makes it possible to test AI-predicted compounds with speed and precision helping to close the gap between drug discovery and preclinical testing. By combining"
Reddit Link 2025-09-04T16:30Z [--] followers, [--] engagements
"Fragile X Research Update: A Turning Point for Treatments and Curative Approaches Fragile X has long challenged families and researchers. Daily life brings uncertainty while science has moved forward step by step. Now research is gaining momentum. Two late-stage clinical trials zatolmilast (EXPERIENCE) and ZYN002 (RECONNECT) are close to reporting results. Either could become the first approved treatment for Fragile X. FRAXAs Curative Therapies Fund is also supporting approaches that aim to correct the root cause including ASO therapy at UMass Chan and CRISPR-based gene reactivation at"
Reddit Link 2025-09-17T17:20Z [--] followers, [--] engagements
"We are excited to share that Anavex Life Sciences announced today that preclinical data of the ANAVEX2-73 (blarcamesine) study in Fragile X syndrome were published in the peer-reviewed journal Scientific Reports. The FRAXA funded study evaluated ANAVEX2-73 in Fmr1 knockout (KO) mice. FragileXReseach FragileXReseach"
Reddit Link 2021-08-26T14:22Z [--] followers, [--] engagements
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